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The Niche

The Niche

Knoepfler lab stem cell blog

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Parkinson’s stem cells

Fig 3i Kikuchi, et al. Nature, 2017 IPS cell Parkinson's

Hope on Parkinson’s front: Japan IPSC trial 1st patient

November 18, 2018 Paul Knoepfler 2

In Parkinson’s Disease patients develop neurological dysfunction as they lose a special kind of brain cell called dopaminergic (or dopamine) neurons. While a number of different approaches to this disease have been studied for decades, nothing has proven particularly successful in […]

GForce_Superhero_logo Parkinson's Disease

Lorenz Studer on Day 1 #ISSCR2018: HESC-based therapies for Parkinson’s Disease

June 20, 2018 Paul Knoepfler 2

One of the highlights of Day 1 of #ISSCR2018 for me so far was the talk by Lorenz Studer (Co-Founder of BlueRock) on the use of human embryonic stem cell (HESC)-derived dopamine neurons for Parkinson’s Disease. Note that for this […]

Dopamine neurons derived from a Parkinson's disease patient's iPSCs (Tyrosine hydroxylase)

On the threshold of cell therapy for Parkinson’s disease

November 13, 2017 Paul Knoepfler 7

By Jeanne Loring There are ten million people in the world who have Parkinson’s disease. 125,000 of these are living in California.  People with the disease often have to step away from their jobs because the main symptoms – tremor […]

Heather_Main

Overview of Yamanaka Talk at #ISSCR2015 by Heather Main

June 25, 2015 Paul Knoepfler 1

ISSCR day one By Heather Main The day of plenary is the most enjoyable in my view. You don’t need to make the choice between sessions and the judgement on the viability of shifting sessions versus staying put and listening […]

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