October 20, 2020

The Niche

Knoepfler lab stem cell blog

prostate cancer

2 min read

Here in the U.S. we just had our big Thanksgiving holiday, but science goes, stem cells keep growing and needing attention, and it’s another weekend chance to catch up on our paper reading. Here’s this weekend edition of recommended reads including news items and pubs. From Cell Stem Cell: Single-Cell Transcriptome Analysis of Uniparental Embryos Reveals Parent-of-Origin Effects on Human Preimplantation Development. and another there on stem cell machinery in cancer: Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy. …Read More

4 min read

A new Nature paper makes the striking claim that neural precursor cells of the brain migrate all the way to prostate tumors. Furthermore, the team led by Claire Magnon claims that these long-distance cellular travelers from the brain not only take up residence in the prostate but also strongly drive progression of the prostate cancer via neurogenesis there. From what I know, this claim goes counter to general principles of animal physiology so if it’s accurate, it’s a huge deal. Other than blood cells, …Read More

2 min read

What are your typical weekend reads? If you are a scientist, they might often include a great deal of science. I always hope I can find time for reading for pleasure too, but about as close as I get to that is the New York Times on Sunday. Here are some recommended science reads for this weekend including approachable media articles on interesting developments. Blood test shows promise for spotting early cancers. In addition to being a cancer researcher, as a cancer survivor myself and …Read More

2 min read

What’s on my mind today on National Cancer Survivors Day as a cancer survivor? 2009 was a bad year for me as in the spring my dad died and then in the fall I was diagnosed with a very serious form of prostate cancer out of the blue at age 42. I then had surgery. The cancer itself made me feel physically sick, but also going through the whole experience including the shock of the diagnosis with a potentially fatal illness and the surgery …Read More