July 14, 2020

The Niche

Knoepfler lab stem cell blog

retinal pigmented epithelial cells (RPE)

2 min read

Masayo Takahashi is a leading stem cell researcher doing translational and clinical research on vision. She’s doing pioneering work on using pluripotent stem cells as a basis for helping patients with vision loss such as due to macular degeneration. She won The Niche’s Stem Cell Person of the Year Award in 2014 and a number of other awards. Last week I did a post on some exciting new clinical trial work starting here in the US by the NIH/NEI, and that sparked a great …Read More

2 min read

Ring the bell for a stem cell milestone. There’s been a whole lot of commotion about the NEJM article yesterday documenting the experiences of three women with macular degeneration who were blinded by non-FDA approved stem cell eye injections of fat stem cells at a business in Florida, but in the same issue of the journal there also was some encouraging stem cell news that came in the form of essentially a mirror image of the bad news paper. We can call it the “stem cell …Read More

2 min read

At the recent RPI stem cell and bioengineering meeting, the Neural Stem Cell Institute’s Sally Temple talked about her group’s intriguing retinal pigmented epithelial cell (RPE) research. With the broad focus of attention in the world of RPEs mostly on those derived from either human ESC or IPSC, it was exciting to here about the adult RPEs that Temple’s group has isolated and characterized (e.g. see this paper). Although only about 3% of cells isolated from the human retina turn out to be retinal …Read More

2 min read

Last week I attended and spoke at a stem cell meeting at Rensselaer Polytechnic Institute (RPI). It was entitled, “Bioengineering and Stem Cell Research”. It was a great meeting with many interesting talks. Below I write about some of the talks and themes of the meeting. Still to come later this week I will do a second post entirely focused on the exciting RPE work of Sally Temple, who spoke at the meeting. One of the major themes of this meeting was, as Mark Noble put it during …Read More