RIKEN CDB

STAP Voted as the Stem Cell Story of the Year for 2014

Stem-Cell-Story-of-2014

When I asked the readers of this blog what they felt was the biggest stem cell story of 2014 in a poll, they overwhelmingly picked the STAP cell scandal. For background on STAP you can toggle through the many STAP cell pieces on this blog here, see a STAP timeline, and a STAP image gallery. Basically, …

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Diverse Stem Cell Person of the Year 2014 Award Finalists

Stem-Cell-Award-Poll-2014

With more than 4,142 votes cast, the readers of this blog have chosen the top 12 finalists for the Stem Cell Person of the Year Award for 2014 from the 27 nominees. You can see the final vote tallies at left. The votes came from more than 50 countries with some interesting geographic patterns (I …

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Yamanaka Interview on Clinical Use of IPSC

Dr.-ShinyaYamanaka

I invited Nobel Laureate Shinya Yamanaka to do an interview on the future of clinical translation of induced pluripotent stem cells (iPSC). He provides some intriguing new insights into the iPSC field and the broader stem cell arena. PK: The Takahashi Team’s active Clinical Study using iPSCs to make RPEs to treat Macular Degeneration has …

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STAP papers blistered by Nature’s own reviewers were then accepted

STAP-magic

The reviews of a STAP paper submitted to and rejected by the journal Science in 2012 were posted at Retraction Watch yesterday. They filled in some gaps in the puzzle of the series of events that led to such flawed science being published in Nature in January 2014, but the reviews also raised more questions. Today, more STAP paper …

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Full Reviews of Rejected STAP Paper Point to Early Signs of Big Trouble

Before the two STAP cell papers were published in Nature in January of 2014, much of the same data was reportedly submitted as single papers to other high-profile journals including Science. In these cases, the proto-STAP papers as we might call them were rejected. But why? Until now we largely could only speculate. However, the reviews …

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Holding Institutions Responsible for Research Misconduct: the recent case of a death of stem cell scientist

By Zubin Master Scientist Yoshiki Sasai, age 52, committed suicide and was found dead on August 5, 2014. Sasai was deputy director of the Center for Developmental Biology (CDB) at RIKEN in Kobe, Japan, and coauthor on two recently retracted Nature papers about a reportedly easier way to make induced pluripotent stem cells. The papers …

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RIKEN fails to reproduce STAP, big CDB shake up expected

STAP-stem-cells

Nikkei is reporting that the RIKEN internal attempt to replicate so-called STAP (acid bath) cells has failed. Update: apparently, although RIKEN calls the efforts preliminary, the team tried to make STAP an amazing 22 times and 22 times it failed. The rumors for weeks in the stem cell gapevine that RIKEN itself could not get …

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STAP News From Harvard? Vacanti Stepping Down as Chair & Going on Sabbatical

Obokata_Vacanti

What’s the deal with Brigham and Women’s Hospital or Harvard Medical School, where STAP cell senior author works, when it comes to the retracted STAP cell papers? I was just writing yesterday in part about how we haven’t really heard anything (news, statements, etc.) from those places about the whole STAP cell mess. In contrast, in Japan …

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Where will STAP cell mess go from here & key unanswered questions

STAP-stem-cells-hope-or-mirage-201x3001

In some ways it’s hard to imagine that it was only just over 6 months ago that Nature published the two STAP cell papers by a collaborative team of Japanese and American researchers. It feels like years have gone by since then because so much has happened related to the STAP mess including the retraction of the …

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