July 12, 2020

The Niche

Knoepfler lab stem cell blog

Shinya Yamanaka

2 min read

The still mysterious BioGatekeeper had challenged Yamanaka’s IPS cell patent claiming that it was obvious. The potential implications were huge given the commercial interest in translating IPS cell technology. For background see here, here, and here. There’s pretty much zero information on BioGatekeeper otherwise. Despite the potential seriousness of this patent challenge, just a few days ago the Patent Trial and Appeal Board (PTAB) denied the challenge so for all intents and purposes BioGatekeeper’s effort is dead. A big hat tip to reader Shinsakan. You …Read More

2 min read

Congratulations to Masayo Takahashi (高橋 政代), MD, PhD, the winner of the 2014 Stem Cell Person of the Year Award. Dr. Takahashi received this award including the $2,000 prize for her exceptional achievements in stem cell research in 2014. She was selected as the winner from a stellar group of top 12 finalists this year. Takahashi leads a team doing high-risk, high reward research that is conducting the first induced pluripotent stem cell (IPSC) clinical study in humans ever. I interviewed Takahashi at the beginning of this …Read More

1 min read

One of the best stem cell meetings each year is the World Alliance Form San Francisco (WAFSF) stem cell conference. It brings together in San Francisco many of the very best stem cell researchers from around the world doing the most cutting edge translational research. You should go! The speakers include Shinya Yamanaka, Masayo Takahashi, Michael Werner, Roman Reed, Susan Solomon, Jonathan Thomas, Edward Lanphier, Emile Nuwaysir, Hiromitsu Nakauchi, and many more top scientists. You can see the amazing program here and register here. …Read More

5 min read

I invited Nobel Laureate Shinya Yamanaka to do an interview on the future of clinical translation of induced pluripotent stem cells (iPSC). He provides some intriguing new insights into the iPSC field and the broader stem cell arena. PK: The Takahashi Team’s active Clinical Study using iPSCs to make RPEs to treat Macular Degeneration has generated a great deal of excitement. Can you please share your perspectives on the importance of this work and the team involved?  SY: This is the first study to apply …Read More