January 18, 2021

The Niche

Trusted stem cell blog & resources

stap細胞

3 min read

STAP is back? Really? No, I don’t believe so, but there’s an interesting development and twist on the STAP cell front. Just a few days ago on January 4, 2017 Dr. Charles Vacanti, the originator of the STAP cells concept, submitted a declaration to the USPTO affirming the belief that STAP cells are real and requesting that the patent office allow the rejected STAP patent application to be reconsidered. I find a number of aspects of this development notable: The declaration says they have generated new data …Read More

6 min read

Today marks nearing the completion of a full circle for one of science’s biggest controversies: the STAP cell fiasco. Today STAP cells are completely refuted with the publication of two new papers in Nature and we know much more–with some notable gaps still–about what went wrong. In January of last year, an international team of collaborators from RIKEN in Japan and Harvard/Brigham & Women’s Hospital (including the lab of Charles Vacanti where the STAP idea reportedly originated) here in the US published two Nature …Read More

3 min read

The Japanese research institute RIKEN has come full circle in a way on the STAP cell scandal. Note that the STAP papers included not only authors from RIKEN, but also from Brigham and Women’s Hospital/Harvard Medical School. With its final report released today (also a powerpoint of images were released including the one showing a figure posted here of reportedly made up data published in a STAP paper), RIKEN seems to now have handled this complicated mess in a relatively rigorous, scientific manner that …Read More

3 min read

The STAP cell mess that began in January of this year has in some ways quieted down. In a broader sense, I believe that STAP is now and will be in the future viewed as a scandal that revealed some less than ideal aspects to the world of biomedical science and publishing. Where does this all stand today? A New STAP-Like Paper? The most recent development is the publication of a new paper pointed out by a number of people to me as perhaps STAP-like. …Read More

2 min read

The reviews of a STAP paper submitted to and rejected by the journal Science in 2012 were posted at Retraction Watch yesterday. They filled in some gaps in the puzzle of the series of events that led to such flawed science being published in Nature in January 2014, but the reviews also raised more questions. Today, more STAP paper reviews have surfaced. ScienceInsider posted a piece with additional STAP paper reviews with these coming from Nature reviewers commenting on what would later become accepted and published by Nature only months later …Read More

4 min read

Before the two STAP cell papers were published in Nature in January of 2014, much of the same data was reportedly submitted as single papers to other high-profile journals including Science. In these cases, the proto-STAP papers as we might call them were rejected. But why? Until now we largely could only speculate. However, the reviews of the 2012 proto-STAP manuscript at Science can now be read at Retraction Watch. As a result of reading the Science reviews, today we know what the reviewers at Science thought …Read More

2 min read

Nikkei is reporting that the RIKEN internal attempt to replicate so-called STAP (acid bath) cells has failed. Update: apparently, although RIKEN calls the efforts preliminary, the team tried to make STAP an amazing 22 times and 22 times it failed. The rumors for weeks in the stem cell gapevine that RIKEN itself could not get STAP to work, even with the help of Dr. Haruko Obokata, have been confirmed by Nikkei. Obokata was first author on both Nature STAP papers, which were retracted. One of …Read More

4 min read

What’s the deal with Brigham and Women’s Hospital or Harvard Medical School, where STAP cell senior author works, when it comes to the retracted STAP cell papers? I was just writing yesterday in part about how we haven’t really heard anything (news, statements, etc.) from those places about the whole STAP cell mess. In contrast, in Japan and at RIKEN there has been a non-stop flood of news and developments involving STAP. Now today I’ve heard from a source that senior STAP cell paper author, Vacanti, …Read More

3 min read

In some ways it’s hard to imagine that it was only just over 6 months ago that Nature published the two STAP cell papers by a collaborative team of Japanese and American researchers. It feels like years have gone by since then because so much has happened related to the STAP mess including the retraction of the papers and the tragic death of one of the STAP authors, Dr. Yoshiki Sasai, last week. Where does the STAP story go from here? Is it over? In a …Read More