October 29, 2020

The Niche

Knoepfler lab stem cell blog

Stem Cells Cerebral Palsy

3 min read

As of October 1, Google was supposed to have banned ads for unproven stem cell clinics and products. This was according to their own new policy. How’s that going? How’s this new Google approach to unproven stem cell marketing working out in the real wild world of the web? To test it, I did over a dozen common searches that in the past would bring up first or second-page results on Google containing several ads for unproven stem cell firms. Overall, for more than …Read More

7 min read

Amongst all that is bouncing around within the stem cell clinic maelstrom out there, one thing stands out for me as the most troubling. I’m talking about for-profit experimentation on children, such as injection of kids with unproven stem cells for autism or cerebral palsy by unproven clinics. In my opinion it’s almost always going to be risky and unethical. Doing any clinical research on children requires extra care and planning even within an FDA-approved clinical trial context. Obviously pediatric clinical trials are crucial, …Read More

3 min read

Some notable newly published Phase II data from the Duke cord blood for cerebral palsy trial unfortunately doesn’t give much reason for optimism that this approach is going to have a substantial positive effect for these kids. The double-blinded, placebo-controlled study did not find a meaningful benefit overall from infusions of autologous cord blood (ACB) for children with cerebral palsy. It didn’t meet its primary endpoint. The study was published in Stem Cells Translational Medicine and was entitled, “Effect of Autologous Cord Blood Infusion on Motor …Read More

4 min read

Dr. Charles Cox at the University of Texas (UT) Health Science Center at Houston is starting a new stem cell-based clinical trial for the treatment of young children with cerebral palsy (CP). There is an urgent need for the development of new treatments for CP. You can learn more about the details of this specific trial here on clinicaltrials.gov. The purpose of this specific study is to compare the effectiveness and safety of banked cord blood to bone marrow stem cells. Dr. Cox, who …Read More