October 19, 2020

The Niche

Knoepfler lab stem cell blog

stem cells Parkinson’s

3 min read

By Jeanne Loring What can you do with cells that live forever and can make every cell type in the body?  The answer is: remarkable things, as new reports of clinical trials using cell types derived from pluripotent stem cells indicate. Pluripotent stem cells are either derived from embryos donated from IVF procedures (human embryonic stem cells- hESCs) or from cells provided by a person, usually blood or skin (induced pluripotent stem cells- iPSCs).  The stem cells are never used for transplantation; instead, they …Read More

2 min read

In the past month or two there has been a steady stream of good news in the stem cell and regenerative medicine world. Here are three examples. Fate Therapeutics announced the first US IND for an induced pluripotent stem cell (IPSC)-related product. Its cleared product, FT500, is an off-the-shelf natural killer-based cancer immunotherapy. I expect more to come in the next couple years so good news now and likely more to come. IPSC-based trials are picking up in Japan too with trials related to …Read More

3 min read

By Jeanne Loring Stem cells boldly go… Last week at the New York Stem Cell Foundation (NYSCF) conference at Rockefeller University in New York City, we announced our collaborative project to study the effects of microgravity on neurons derived from patient-specific induced pluripotent stem cells.  The press release is here. Susan Solomon, the CEO of NYSCF, announced the unprecedented collaboration:  NYSCF and San Diego’s Summit for Stem Foundation (Summit) are providing the cells and designing the experiment. Space Tango, based in Kentucky, developed the …Read More

2 min read

2018 has started quickly on the stem cell and regenerative medicine research front with many interesting new papers and a lot of headlines. You can see my predictions for this year here. Below is a list of some of the more notable papers and striking news headlines. Note that just because I listed a news headline doesn’t mean a fan and in some cases below I include some words of commentary. I’ve also thrown in a few more rando papers of interest to me. …Read More