stem cells vision loss

Masayo Takahashi (高橋 政代): exciting vision work advancing including with photoreceptors

Dr.-Masayo-Takahashi-高橋-政代.

Masayo Takahashi is a leading stem cell researcher doing translational and clinical research on vision. She’s doing pioneering work on using pluripotent stem cells as a basis for helping patients with vision loss such as due to macular degeneration. She won The Niche’s Stem Cell Person of the Year Award in 2014 and a number …

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Stem cell pioneer Masayo Takahashi (高橋 政代) leaves RIKEN

Masayo-Takahashi

In a surprise, Dr. Masayo Takahashi has announced that she has left RIKEN. Takahashi indicates she will be new President of a company called Vision Care, Inc. as part of the Kobe Eye Center. I’ve pasted a picture of Takahashi’s Tweet with translation more toward the bottom of the post. A big thanks to Piero …

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Japan stem cell clinical studies rapidly piling up

Shibata-et-al.-Cell-reports-2018-corneal-structures-made-from-hIPSCs

Japan is a leader in stem cell and regenerative medicine research, and in particular in clinical translation toward the bedside. Induced pluripotent stem cell (IPSC)-based investigational therapies are rightly an area of focus in Japan given their invention by Nobel Laureate Shinya Yamanaka. Small clinical studies based on IPSC have been initiated there for several …

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Stem cell news bites: Astellas trial, cystic fibrosis claim, a few cool papers

Matoba-et-al-Figure-2c-2018

Stem cell news is always burbling up, sometimes right there in front of us on the web and other times via networks of people. Astellas news. Some may remember there used to be this pioneering stem cell biotech called ACT, which then became Ocata, and finally was acquired by the big company Astellas. One of …

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Grading 3 stem cell media reports on clinical science: vision, MS, & paralysis

Rosenzweig-et-al-Nature-Medicine-2018-part-of-Fig.-1

What is stem cell media? When us scientists hear the phrase “stem cell media” we usually think about the liquid food that we feed our stem cells in the lab, which resembles a kind of nutrient-rich Kool-aid, but another kind of stem cell media consists of the news coverage of stem cells. This other kind …

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Adverse event in IPS cell (ips細胞) trial for vision loss in Japan: initial perspectives

Takahashi-IPS-transplant

A team of researchers at RIKEN and Kobe City Medical Center reported at a press conference today a serious adverse event in a clinical trial participant receiving an induced pluripotent stem cell (IPS cell)-based therapy for vision loss. According to Japan Times and Yahoo! Japan (in Japanese), the patient in question in the IPS cell …

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Great news: FDA gives ACT the green light bringing hope to millions of people with blindness

advanced-cell-technology

The FDA has given Advanced Cell Technology (ACT) the go ahead to begin their clinical trial using retinal progenitor cells derived from hESC by clearing the company’s IND application, bringing hope to those with vision loss and even blindness. The trial will be a combined Phase I/II to treat Stargardt’s Macular Dystrophy and has huge …

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