January 24, 2021

The Niche

Trusted stem cell blog & resources

Stem Cells

4 min read

Who are the top stem cell and regenerative medicine influencers to follow on Twitter and elsewhere in 2019? Terrapin asked this kind of broad question to some within our community about 5 years ago and came up with a Top 50 list of stem cell influencers, which I like to joke I was “at the top of” because I was #50 and they listed us in reverse order. What about today and soon in the coming year in 2019? Who are the major regenerative medicine …Read More

3 min read

I keep a yearly hub of stem cell & regenerative medicine meetings here on The Niche. Below I’ve pasted the list for 2019, which continues to grow. If you don’t see yours listed, send me an email with the info including a link (knoepflerATucdavisDOTedu). These meeting listings are not endorsements and I try to make this list fairly comprehensive, but if you see a clearly predatory meeting, please email me and I’ll look into taking it off the list. 2019 stem cell and regenerative …Read More

3 min read

Over the weekends I try to catch up on more diverse reading and sometimes come up with a list of stuff I want to get to during this time, but I also put together weekend reads usually on Fridays as a kind of TGIF on The Niche for the wider audience here. So here’s the weekend reads for this Friday the 13th including some wacky stuff at the end. Anti-Aging efforts got some play in the media including this LA Times piece. Here’s the …Read More

3 min read

There are now so many clinics selling non-FDA approved stem cell offerings across the U.S. that tens or hundreds of thousands of patients are at risk. How did we get here? What if we had a way of understanding how stem cell clinics spread across the U.S. in the first place? For example, an animated map showing the spread of stem cell clinics selling non-FDA approved “treatments” across the U.S. would be useful. With publication of our new paper, the recent work of Leigh Turner …Read More

2 min read

Snopes said what about stem cells? A brief search of Snopes for “stem cells” produces some wacky claims about our favorite cells. They tackle some stem cell myths floating around out there that overlap somewhat with a post I did about 5 years ago on stem cell myths. I’ve listed below the search results on the first page from Snopes for stem cells, with below each one my thoughts on it. Should You Save Baby Teeth for Stem Cells? Eh, maybe…maybe not. Can a …Read More

4 min read

What happens following pluripotent stem cell transplants into the brain? Are human IPS and ES cells going to function similarly in this context? We recently published a new translational paper on the behavior of human pluripotent stem cells when transplanted into the adult mouse brain in collaboration with my great UC Davis colleague, Dr. Veronica Martinez-Cerdeno. Martinez-Cerdeno V, Barrilleaux B, McDonough A, Ariza J, Yuen B, Somanath P, Le C, Steward C, Horton K, Knoepfler P. Behavior of xeno-transplanted undifferentiated human induced pluripotent stem cells is …Read More

3 min read

It’s fun and useful for me to learn about the readers of this blog in terms of who they are and what their interests are in terms of the types of posts that I do. Below are the results of two recent reader surveys that I did to get this kind of information. The two polls got 162 and 192 responses, respectively. Before I get to discussing the results, I also included a prize/raffle element to this survey whereby I would choose one winner …Read More

3 min read

It was just over a decade ago that I started making websites and it’s been a wild ride. My first site was at the domain name www.chromatin.com, which I was fortunate to have been able to get for a good deal way back when…I think in 2005. You can see here an early 2007 copy of the archive of one of my first versions of the Knoepfler lab website at chromatin.com. I first put up that website around the time that I moved here to …Read More

4 min read

Do we own our cells? Do we have some intrinsic right to them once they are outside our bodies? One of the arguments I hear most often from physicians at stem cell clinics and some clinic patients is that patients have an inherent right to ownership and almost unlimited use of their own stem cells, but over the years my own reading on this issue has suggested that actually their assumptions are not necessarily the actual reality. At that link above you can read about some pretty …Read More

2 min read

Keep your hands off of my cells! At least, that is what many are telling the FDA regarding stem cells. The FDA issued four draft guidances related to stem cells in the past year or so, held two public stem cell meetings, and now must decide what it is going to do with an out of control direct-to-consumer stem cell clinic industry. In part it will need to sort through all public comments from the meeting and those submitted online. There are 4,251 comments …Read More