Stimulus-triggered fate conversion of somatic cells into pluripotency

RIKEN Report Is Virtual Acid Bath of Criticism for Obokata

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RIKEN Institute in Japan has formally announced the complete findings of its investigation into the STAP cell research,  Haruko Obokata, and Nature papers. RIKEN almost entirely blamed Obokata for the STAP mess in this report and they didn’t mince words. The RIKEN report alleged that Obokata had engaged in two instances of “research misconduct” as …

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STAP Cell Nature Papers: Cases For & Against Retraction

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What next for STAP? Is retraction of the two papers on the near horizon? It has been two months now since Nature published the two papers on STAP cells and STAP stem cells. There has been a storm of controversy surrounding these papers and the claims they made to easily produce the most powerful of …

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Clues as to the real STAP cell scoop: a trio of biosci traps

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I don’t really hear from almost anyone who fully believes in the STAP cell thing anymore. The most common thing I do hear is from people assuming STAP is largely or entirely wrong and asking, “what really happened?” There’s still a chance that STAP is real, but if I were in Vegas or at the …

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Nature Rejects Paper Reporting that STAP Does Not Work

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Dr. Ken Lee’s lab has done some very important validation attempts on STAP cells and has posted them on ResearchGate. To my knowledge, his lab’s STAP experiments are the ones in the public domain that most closely matched the methods of the Nature STAP papers. Dr. Lee submitted the work to Nature Brief Communications Arising …

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Reactions to New On-Line Vacanti Lab STAP Cell Protocol

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The Vacanti Lab at Brigham and Women’s Hospital/Harvard Medical School has now posted online their own version of the STAP cell production protocol. The thing that first struck me most strongly about this published protocol is that it is not the same protocol reported in the Nature papers and it also is not the same …

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Vacanti to Speak on STAP Cells at Harvard on April 1

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Dr. Charles Vacanti is scheduled as a special guest speaker on April 1 at Brigham and Women’s Hospital. He’ll be speaking on STAP cells. See image below of the announcement. The title of his talk is “Tissue Engineering and STAP Cells”. It is part of the Brigham and Women’s “Leaders in Regenerative Medicine Seminar Series”. Online …

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RIKEN Initial PR Reaction to STAP Cell Fiasco

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The controversial STAP stem cell papers published in Nature had authors both from RIKEN in Japan and Brigham and Women’s Hospital/Harvard. What is the RIKEN interim take on the STAP cell situation? We’ve had pretty much silence from Harvard itself on this matter publicly. Dr. Charles Vacanti, senior author on one of the STAP papers, …

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Beginning of End for STAP Cell Story? Possible Outcomes

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A host of problems have emerged related to the two Nature papers on STAP cells and other publications by some of the same authors. It’s only been just shy of 6 weeks since these papers came out, but doesn’t it feel like about 5 years? Where will this all end? (update in 2020: closer to …

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Reactions to RIKEN’s STAP cell protocol

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A small group of the STAP authors via RIKEN have now released a detailed protocol also available at Nature Protocol Exchange for making STAP stem cells entitled “Essential technical tips for STAP cell conversion culture from somatic cells”. This comes about 5 weeks after publication of their Nature STAP stem cell papers. 2020 update: With the 4th and …

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What does future hold for STAP stem cells? Possible paradox

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What will the future bring for STAP stem cells? Let’s look into a stem cell crystal ball. We are now one month out from the original publication of the papers. When we are three or six or twelve months out from their publication will independent labs have succeeded in replicating the method? It’s possible, but …

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