teratoma

What is a teratoma? Research & treatment

What is a teratoma? human stem cell teratoma knoepfler lab sm

Sometimes on The Niche or while teaching students as a professor here at UC Davis School of Medicine, I’ve been asked: What is a teratoma? Not all tumors are created equal and some like teratomas are particularly unusual. Exactly what is a teratoma? Teratomas are germ cell tumors. What this means is that the cells …

What is a teratoma? Research & treatment Read More »

Stem cell transplants: hIPSC and hESC behave similarly in brain & often fuse with host cells

Martinez-Cerdeno-Figure-6

What happens following pluripotent stem cell transplants into the brain? Are human IPS and ES cells going to function similarly in this context? We recently published a new translational paper on the behavior of human pluripotent stem cells when transplanted into the adult mouse brain in collaboration with my great UC Davis colleague, Dr. Veronica Martinez-Cerdeno. …

Stem cell transplants: hIPSC and hESC behave similarly in brain & often fuse with host cells Read More »

Myth of Perfect Stem Cell: meaning for ACT, Geron and field

in-science-we-trust

  There are a lot of myths in the stem cell field, some even embraced by some stem cell scientists such as the notion that teratoma are always benign. But when we start talking about translating stem cell technology into the clinic, to the bedside, it is especially important to cast aside our myths, no …

Myth of Perfect Stem Cell: meaning for ACT, Geron and field Read More »

The trouble with teratoma: a stem cell paradox

Teratoma

The trouble with the risk of teratoma presents a stem cell paradox. Stem cells possess two traits lacking in other cells: self-renewal and pluripotency. This duo of defining functions is key to the ability of stem cells to be used to treat patients via regenerative medicine. A paradox exists because while self-renewal and pluripotency are both …

The trouble with teratoma: a stem cell paradox Read More »

Anonymous stem cell scientist frankly answers questions about the field

Anonymous-scientist-stem-cell-field

Here an anonymous stem cell scientist frankly answers questions about the field in an interview with me. Of course I have to ask you about the recent U.S. court ruling essentially declaring all federal funding of human ES cell work illegal. What’s your take on this? ANSWER: The ruling has so many flaws in it. …

Anonymous stem cell scientist frankly answers questions about the field Read More »