June 4, 2020

The Niche

Knoepfler lab stem cell blog

The Niche blog

5 min read

What happens next to He Jiankui (贺建奎) or as some people now refer to him, the “CRISPR baby guy”? China has a challenging situation to resolve here, but such conflicts between scientists and governments have happened regularly in history. When scientists go “rogue” (i.e. don’t conform to norms or ethical standards in an extreme way or potentially break laws), governments are often unsure what to do. Also, who decides what’s “rogue”? Where is the line between positive transformative science and something that is really wrong? …Read More

4 min read

If it seems to you like dramatic cautionary tales about CRISPR accompanied by all sorts of media are coming at us more frequently, it’s not your imagination. In the latest yesterday, it was reported in a new paper led by Allan Bradley that CRISPR-Cas9 results in sometimes large-scale chromosomal lesions at or even away from the target locus. The media have really sunk their teeth into this one, just as in past situations where CRISPR has reportedly encountered anything from bumps in the road to …Read More

2 min read

It was interesting to see that this blog The Niche was cited in the lawsuit filing by the DOJ in the U.S.A. vs. California Stem Cell Treatment Center, Cell Surgical Network (CSN), et al. case. Yeah, that lawsuit. This suit is part of the DOJ action yesterday that along with the other suit against US Stem Cell seeks permanent injunctions against these firms related to their use of stem cells. Here’s the passage in paragraph 60 of the suit by the DOJ citing this interview that I …Read More

2 min read

I started The Niche blog in largely its current form early in 2010, and now 7+ years later we’ve hit two big milestones recently. First, about a month ago, we reached 10,000 comments made on the blog. Thanks for being involved in the discussion on the Niche blog! Second, we reached 7,000,000 total page views on the Niche. Considering early on, we were getting something like 7 readers a day, to get to seven million is quite something. It’s been an exciting, wild ride …Read More

3 min read

2,000 is a big number. As of this week I’ve now published 2,000 posts here on The Niche since I started back in early 2010. I can’t quite believe it myself. To celebrate that milestone, I have revamped The Niche in terms of its organization and style with the help of a very skilled web developer. You might have noticed some of these changes around here. I hope you like them. The site should be speedier for one thing. We are also nearing another …Read More

1 min read

After 5 plus years as “Knoepfler Lab Stem Cell Blog”, we are now going by a new, broader name for the blog, The Niche. The Niche name better represents the sense that this site is a home and community including contributions by other writers and also commenters. I’m still working on a logo for The Niche. As The Niche continues to evolve look for it to include a wider range of contributors. As you may have noticed we have an increasing number of posts …Read More