August 7, 2020

The Niche

Knoepfler lab stem cell blog

transdifferentiation in vivo

4 min read

What if you could reprogram cells inside of an organism to a different fate and, for instance, make IPS cells? We can, right? But when most of us think about making induced pluripotent stem (iPS) cells, we imagine it all happening in a little plastic dish in our labs or in our colleague’s labs, not in an actual organism. A cancer research team at the Spanish National Cancer Research Center took a very different approach reported in a hefty Nature article. They made iPS cells inside of …Read More

4 min read

The leading cause of death in America and many other countries of the world is cardiovascular disease (CVD) including heart attacks and strokes. In fact, CVD kills and disables more people than most often top killers combined including cancer. The myth that CVD is a “man’s disease” only makes the situation worse as in reality CVD is a top killer of women as well, killing dramatically more women than breast cancer, for example. A new paper out yesterday from a Gladstone team led by Deepak …Read More