transdifferentiation in vivo

Stem cell journal club: dishing on Nature paper on making iPS cells inside mice

What if you could reprogram cells inside of an organism to a different fate and, for instance, make IPS cells? We can, right? But when most of us think about making induced pluripotent stem (iPS) cells, we imagine it all happening in a little plastic dish in our labs or in our colleague’s labs, not …

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Transdifferentiation meets gene therapy to tackle heart disease

The leading cause of death in America and many other countries of the world is cardiovascular disease (CVD) including heart attacks and strokes. In fact, CVD kills and disables more people than most often top killers combined including cancer. The myth that CVD is a “man’s disease” only makes the situation worse as in reality CVD …

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