July 10, 2020

The Niche

Knoepfler lab stem cell blog

transdifferentiation

2 min read

How does one keep up with all the regenerative medicine and stem cell happenings? There is always something happening in the stem cell and regenerative medicine field ranging from science to policy matters. This post is an update on some recent stem cell happenings that I see as notable or interesting. New Pubs Direct reprogramming pub. One of the more interesting recent papers was from direct reprogramming guru Marius Wernig as his team came out with a new transdifferentiation paper that strikingly reports conversion …Read More

4 min read

CRISPR and IPS cells are two of my favorite things so when they come together as in a cool, new paper from Sheng Ding’s lab, I’m excited to read it and curious as to what the scoop is. Since 2006-2007 when mouse and human reprogramming were first reported, many different methods have been explored to make induced pluripotent stem (IPS) cells. Along the way we’ve all learned quite a lot about how pluripotency is regulated, whether it is in the context of maintenance or …Read More

2 min read

Ready for some stem cell good news? It can be difficult at times in a cutting edge field like stem cells in terms of keeping upbeat about hopes of rapid translation to help patients with real, proven therapies. It takes a long time, money, dedication, and even a bit of luck for the researchers and biotech companies out there. It’s a challenging path with many possible roadblocks and landmines. For instance, I recently wrote about how many stem cell stocks are not doing well. …Read More