June 4, 2020

The Niche

Knoepfler lab stem cell blog

Utx1

4 min read

What is “radically deterministic” cellular reprogramming? Jacob Hanna’s lab recently published a very high profile Nature paper on nearly 100% efficient iPS cell formation based on targeting a factor called Mbd3. This super efficiency is a major departure from past reported efficiencies. This morning here at the Till & McCulloch Stem Cell Meeting in Banff, Hanna gave an intriguing talk telling us more about his lab’s efforts in this area. He also fielded some incisive questions from the audience (including 2 from me) after …Read More