August 8, 2020

The Niche

Knoepfler lab stem cell blog

VSEL

4 min read

One of the more controversial areas in the stem cell field has been over a Sasquatch like stem cell type that only a handful of researchers have been able to find and study: very small embryonic-like stem cells (VSELs). A Sasquatch is a generally thought to be mythological creature from the Pacific Northwest area of the US where I grew up, also sometimes called Big Foot. Some folks believe in the Sasquatch. Some people believe in VSELs too.  I’m more interested in what you think …Read More

4 min read

Are MUSE cells for real? Stem cells come in different types that vary in a key property called “potency”, but very few are pluripotent. The more potency, the greater the flexibility of a stem cell to make other cell types. Flexibility in the cellular world is power. The most powerful stem cells generally used are called “pluripotent”, which refers to a special kind of stem cell that can make all 200+ other types of cells in the body through differentiation. Pluripotent stem cells are hard …Read More

5 min read

I recently did a Q&A interview with NeoStem CEO Dr. Robin Smith. I posted Part 1 of that interview a few days ago here. Now we have part two focused on VSEL, ES cells, and iPS cells. PK: I frequently have readers of my blog ask questions about VSEL. They seem puzzled and unsure of what to think about these cells and their potential clinical use. Can you tell us in a nutshell what they are, why NeoStem is making such a big bet …Read More