weekly reads

Weekly reads: stem cells to gametes, no PRP benefit, WHO CRISPR, pubs

making human eggs from stem cells

The paper of the week is from Science on making ovarian follicles and actual eggs from stem cells. It’s just in mice, but this line of work tends to stir people up. We’ll dive into that in a moment. But first some good news. We’re up to 146 subscribers on our stem cell YouTube channel …

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Weekly reads: life extension & BioViva, clinics & anti-vax, axolotls, systemic CRISPR

BioViva CEO Liz Parrish in YouTube video.

Let’s start off today’s recommended reads with the topic of life extension. No controversy there, right? This comes to mind because of a new preprint from BioViva, Liz Parrish, and George Church. I’m hoping to cover this on our Stem Cell Channel on YouTube.  Gene therapy and life extension research The preprint is entitled, “New …

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Weekly stem cell reads: Pew, cord cells for COVID, more

large b cell lymphoma

Sometimes the recommended weekly stem cell reads are just a bunch of papers I find intriguing, but more often they include at least one or more things that are not necessarily “recommended”. Instead these are items that stimulate discussion and debate. Today’s post includes one such complicated area on cord MSCs related to COVID-19 plus …

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Weekly reads: court case, cancer stem cells, skin, pluripotency, & more

chen et al fig 1e nat comm 2021 phc1

This was a busy week for me working on a grant due Friday and a bunch of other stuff including happily analyzing a bunch of data, but there were tons of interesting papers recently including on pluripotency. California stem cell clinic court case on in the background Along the way this week I was occasionally …

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Weekly reads: oncodevelopmental factors, iPSC cancer vaccine, more

stem cell vaccine paper ouyang et al

One of my main research interests is in oncodevelopmental factors. These include factors that are important both for normal stem cell biology and development as well as driving cancer when misregulated. One example includes the MYC family of proto-oncogenes. When I was a postdoc I got especially interested in trying to understand the normal role …

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Weekly reads: stem cells for spina bifida & diabetes trials, pubs

arthur the dog helps test stem cells for spina bifida

It’s always great when there’s good news in the stem cell field and a new trial of stem cells for spina bifida here at UC Davis School of Medicine is very encouraging. So I’ll lead off with this story. Stem cells for spina bifida This pioneering work is led by Drs. Diana Farmer and Aijun …

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The Niche reads: COVID, new INDs, clinic suits, papers

duan et al current biology 2021 fig 1b, The Niche recommended reads

Here are my recommended weekly reads for The Niche readership for early February 2021 including COVID-19 and stem cell lawsuit updates, papers, and more. How many papers do you end up reading each week or month these days? More or less than before the pandemic? COVID-19 updates New diabetes cases linked to covid-19, WaPo  ICYMI …

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Recommended reads: jobs, FDA letter, & The Niche new look

the body building fda letter the niche

During the week as I’m doing other stuff I keep my eyes open for interesting things to read, including over the weekend about stem cell research, COVID, CRISPR, and more for The Niche weekly recommended reads. This week a lot was going as we updated The Niche site to our new theme and format. I …

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Recommended reads: CRISPR for Sickle Cell, Parkinson’s, & more

victoria gray family crispr sickle cell b

I’m playing catch-up on some reading given how busy I’ve been and this includes a groundbreaking NEJM pub on CRISPR for Sickle Cell and Thalassemia. CRISPR for Sickle Cell From December, here’s the key paper in the NEJM: CRISPR-Cas9 Gene Editing for Sickle Cell Disease and β-Thalassemia. There’s a lot to like about this clinical …

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Weekly reads & paper of the week: gene-editing vs. aging

koblan et al 2020 nature gene editing progeria

The paper of the week reports using base-editing, a kind of gene-editing, to reverse mutations associated with rapid aging syndromes, generally called progeria, but there are a lot of other interesting pubs to recommend for reading this week. I go over it all in this post. Gene-editing to fight premature aging syndromes In vivo base …

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