June 2, 2020

The Niche

Knoepfler lab stem cell blog

xanthine reprogramming

3 min read

A new patent has been awarded for a very unusual method claimed for making induced pluripotent stem (iPS) cells. The patent, No. 8,759,098, claims that a single non-genetic chemical agent, xanthine, can by itself reprogram adult stem cells (ASC) into iPS cells (aka iPSCs; see image they released at left). Surprising, huh? Another notable element to this story is the identity of the patentee: Dr. James L. Sherley. Sherley fought a court battle (Sherley v Sebelius) with the Obama administration seeking to ban all federal funding for embryonic …Read More