August 12, 2020

The Niche

Knoepfler lab stem cell blog

Xiangjin Kang

6 min read

Cut, modify, paste… It’s kind of a CRISPR mantra for those of us using gene editing in the lab. But it’s supposed to be happening just on DNA, right? Now it appears that someone on a team of human embryo CRISPR researchers possibly got carried away with the cutting-modifying-pasting mindset to take it beyond DNA to also do so with passages of another researcher’s published work that they apparently slightly modified and put into their own paper without any acknowledgement. The 2016 article in question containing plagiarized …Read More

3 min read

A new paper was recently published on CRISPR of human embryos for genetic modification. I’ve got to read this publication more carefully, but here’s a quick initial take on this human CRISPR 2.0 study. The paper is Kang, et al. and is entitled “Introducing precise genetic modifications into human 3PN embryos by CRISPR/Cas-mediated genome editing”. This is only the second paper reporting genetic modification of human embryos. The first paper, also from China, created quite a stir last year and reported a lot of technical …Read More