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Weekly reads: hit pause on human life, CIRM pause, 23andMe data, blast from the past

October 13, 2024 / Professor Paul Knoepfler, Ph.D. / 20 Comments

Remember cryonics, the idea that you could hit pause on human life? This relies on the super-cold power of liquid nitrogen or some other ultra-freezing method. Apparently cryonics is still a thing and there are people with even just their heads frozen. A new story claims a different way to hit the pause button on […]

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Landmark decision: FDA Approves 23andMe Genetic Test

February 19, 2015 / Professor Paul Knoepfler, Ph.D. / 2 Comments

23andMe CEO, Anne Wojcicki, just emailed 23andMe customers (me included) with the big news that the FDA has approved the company to offer Bloom syndrome carrier status reporting. As Wojcicki points out, this is the first time ever that the FDA has granted authorization of a direct-to-consumer genetic test. This is a huge deal. Why

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23andMe and the FDA: Perspectives on Warning Letter

November 27, 2013 / Professor Paul Knoepfler, Ph.D. / 5 Comments

What’s the deal with this week’s FDA Warning Letter to 23andMe? First some background. I’m a researcher who studies stem and cancer cell genomics and epigenomics. I’m also a human being who has battled prostate cancer and is curious about my genome. With this background, I decided some time ago to take the plunge and experience what

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Take a medical selfie: a taste of your own medicine

December 6, 2015 / Professor Paul Knoepfler, Ph.D. / 1 Comment

“Take a Selfie”, has become a catch phrase in pop culture. There is a preoccupation with capturing one’s own existence and key moments in pictures. Another trend is a DIY culture including taking initiative with one’s own health. When combined together we are in the midst of a larger trend in medicine where patients will

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Nita Farahany Interview on Human Germline Modification: Defining A Road Forward

July 28, 2015 / Professor Paul Knoepfler, Ph.D. / 1 Comment

The topic of heritable human genetic modification has been heating up recently. Prominent scientists, ethicists, and legal scholars have being weighing in, and there is a range of attitudes. Some favor a complete, moratorium including even lab work, while on the other end of the spectrum there are those who have a more liberal perspective. Many

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Apple getting into the genomics biz?

May 8, 2015 / Professor Paul Knoepfler, Ph.D. / 2 Comments

Could Apple computers be getting into the genomics biz? In March, I was thinking it’d be fun to do an April Fool’s Day post. I wrote the following as a possible satire spoof piece title but never had a chance to do an actual post: iPhone 7 To Come With iPhone 7ATGC Version with Personal

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George Church on Germline Human Genetic Modification

March 9, 2015 / Professor Paul Knoepfler, Ph.D. / 17 Comments

I recently interviewed leading genomics scientist George Church on the ways that trends in genomics are changing our world. We also discussed the possibility of heritable human genetic modification. These days we more often call this “CRISPR babies.” His answers suggest that genomics and gene editing are poised to radically change our world. They could literally

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