July 13, 2020

The Niche

Knoepfler lab stem cell blog

Paul Knoepfler

4 min read

What’s new in the stem cell, cell therapy, and regenerative medicine world as well as biomedical science more generally including cancer? There’s quite a bit of news as reflected in media pieces and new pubs. Today’s post is focused on pubs that just came out. For last week’s recommended reads see here. Oct4-Sox2 Nucleosome Binding & Impact in mESCs This is one of my favorite papers of 2020 so far, coming to us from Science. Mechanisms of OCT4-SOX2 motif readout on nucleosomes. I knew from …Read More

3 min read

Clinical trials using organoids are still rare and a Clinicaltrials.gov search for such organoid work largely brings up in vitro studies. A new clinical study in Japan where organoid material will actually be transplanted into patients is causing a lot of excitement. Masayo Takahashi (高橋 政代) is a pioneer in stem cell-based clinical trial work and more specifically induced pluripotent stem cell (IPSC)-based trials. Her new clinical study is another groundbreaking step in that it is organoid based, in this case for Retinitis pigmentosa. …Read More

1 min read

Note that this is post “সস্য কোষ (স্টেম সেল) কাকে বলে?” in Bengali is one part of our “Stem Cells Not Lost in Translation” series. You can see the full series of our stem cell white paper in the other 34 languages here. সস্য কোষ (স্টেম সেল) কাকে বলে? মানবদেহে শত শত বিভিন্ন ধরণের কোষ (সেল) রয়েছে যা আমাদের প্রতিদিনের স্বাস্থ্যের জন্য গুরুত্বপূর্ণ। এই কোষগুলি প্রতিদিন আমাদের দেহকে চালিত রাখার জন্য কাজ করে, যেমন আমাদের হৃদয় ধরফর করে, মস্তিষ্ক চিন্তা করে, কিডনি আমাদের রক্ত …Read More

2 min read

A few times a month I do a recommended reads kind of post on more than just stem cells, which people seem to appreciate as a condensed list of new science and medicine. Scientists might ask each other, “what’s in your to-read list?” rather than “what’s in your wallet?” Here are some of the things I’m hoping to get to in coming days or have already taken a look at that seem worth a read. If you want to see last week’s reads here …Read More