What are adult stem cells & their clinical applications?

mesenchymal cells

When someone uses the term “adult stem cells” you might think that simply means stem cells from adults. However, it’s not that simple. The goal of today’s post is to help you get all the key facts about adult stem cells. This includes the different types of adult stem cells and their clinical potential. What …

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Our new paper assessing trials of cell therapy for COVID-19

stem cells for covid 19 kim knoepfler 2021

After the COVID-19 pandemic started clinical trials quickly sprouted up to test various kinds of cell therapy for COVID-19 including stem cells. The most common rationale for this approach is to suppress damaging overactive immune responses. Trials of cell therapy for COVID-19 including stem cells I’ve written quite a lot about these cellular medicine and …

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Weekly stem cell reads: Pew, cord cells for COVID, more

large b cell lymphoma

Sometimes the recommended weekly stem cell reads are just a bunch of papers I find intriguing, but more often they include at least one or more things that are not necessarily “recommended”. Instead these are items that stimulate discussion and debate. Today’s post includes one such complicated area on cord MSCs related to COVID-19 plus …

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Duke & Cryo-Cell plan big stem cell clinic for kids for unproven infusions

cryo cell duke stem cells autism cp

Duke Professor Joanne Kurtzberg’s clinical work on umbilical cord blood for autism and cerebral palsy (CP) involves a partnership with a publicly-traded cord blood banking firm called Cryo-Cell. Kurtzberg is also the Medical Director at the firm. In addition they have intellectual property in this area. The Duke team’s efforts, including those done outside of …

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Weekly reads: cancer stem cells & other pubs plus a puzzler

kyu yum nature cancer stem cells niche

Cancer stem cells are one of the most interesting areas of research, intersecting the stem cell and cancer fields. Today’s weekly reads post highlights some new cancer stem cell articles along with some other interesting papers. I also note a recent weak stem cell clinical trial paper that is not a recommended read but is …

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US Stem Cell clinic loses appeal, could impact pending Cali case?

us-stem-cell-clinic

The FDA filed two suits against unproven stem cell clinic firms in 2018 seeking permanent injunctions against them including US Stem Cell in Florida and Cell Surgical Network, et al. here in California. There’s been a major new development in this story that I see as good news. Court rejects US Stem Cell clinic appeal …

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Weekly reads: escape to New York, CRISPR baby patents, ISSCR guidelines, pubs

the high line in manhattan

My to-read list this weekend includes a range of papers along with various news & media including a report of two US research groups aiming to get CRISPR baby patents. More on that below. At long last a trip + fun thing to do in NYC Last week I took my first trip in more …

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Risks rise as ISSCR drops strict 14-day rule on human embryo growth in the lab

mouse embryos grown outside the lab

Something called the 14-day rule on growing human embryos in the lab helped keep a tough question in check for a long time: when is it ethically wrong or just practically unwise to continue growing a human embryo for research? There is no good answer based on science or anything else. ISSCR moves beyond strict …

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Weekly reads: Orchard punts on life-saving SCID trial, cardioids with cavities, more

cardioids stem cells

Sometimes things in the stem cell world get complicated and this week is no exception with news of Orchard Therapeutics dropping a seemingly life-saving clinical trial. There are hundreds of kids who could possibly benefit. Rotten apple decision from Orchard Therapeutics From David Jensen at California Stem Cell Report we have something of a scoop: …

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