Why De-extinction of Woolly Mammoths is Still a Bad Idea

George Church De Extinction Mammoth

The push for de-extinction of woolly mammoths is a perfect example of when one notion can be both fun and a rotten idea. You can’t let the coolness push you down a bad path. De-extinction of Woolly Mammoths It was almost exactly 8 years ago that I first wrote about why the buzz surrounding the …

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$7.8 million verdict in stem cell clinics case against Neil Riordan

RMI

Those who follow the stem cell field might be familiar with stem cell clinic operator Neil Riordan. According to a recent press release and some news reports, Riordan just had some bad news in court related to a stem cell clinic in the U.S. Stem cell clinic lawsuit As background, why do those running stem …

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Weekly reads: Bezos & stem cells for anti-aging, Myc, more

young blood, stem cells anti-aging

Stem cells may have anti-aging properties, but they are unlikely to be a real fountain of youth. Even so, people are obsessed with aging and stem cells regularly are thought of as “the ticket” for fighting aging. I’ll start today’s recommended reads with that topic and then go on to list some interesting papers of …

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Human cloning is more likely now but would you take the big risks?

human cloning

I’ve been following the research related to human cloning now for more than a decade. Is human cloning more possible at this point? How do we even define such cloning? Did you know there are two types? The goal of this post is to educate you and in the process answer such questions. What’s in …

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Weekly reads: vision, MyoD, liver regen, more

fish-eyes-from-stem-cells, stem cells for vision

I love stem cell research but experiments that have practical possible future applications in medicine like for vision loss are especially interesting to me. On the other hand basic research on core transcription factor mechanisms like by MyoD also really grab me. We cover some of this stuff and other ground in today’s recommended reads. …

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Weekly reads: CTCF, Sox transcription factors, Clinic fires back, more

heart stem cells

I’m taking a short break today from working on a big grant to put out this weekly reads post including on Sox transcription factors, cord blood paper controversy, and other interesting papers such as one on CTCF and chromatin domains after mitosis that really struck me. I can actually see blue sky today here in …

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Congrats to Lusubilo Mwalilino, the winner of our stem cell video contest

Lusubilo Mwalilino, the winner of our stem cell video contest

Every year I run a number of contests here on The Niche and the most recent is a stem cell video contest.   I’m pleased to announce the winner of our contest is Lusubilo Mwalilino. You can see her video entry above, which is now part of our stem cell YouTube channel. Please check out …

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Recommend reads: stem cell niche, Georgia & FTC on clinics, more

Georgia AG Chris Carr

This blog is called The Niche so publications on the stem cell niche often catch my eye even if that’s not something my own lab directly works on much. So today’s recommended reads will start with two papers on the stem cell niche. The first one focused on the niche  gone wrong. The stem cell …

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FDA should freeze Duke EAP & probe $58 million Cryo-Cell deal linked to it

cryo cell infusion clinic marketing

I recently found concerning SEC filings from the biotech Cryo-Cell about a deal it has with a Duke team for infusions of children with unproven umbilical cord cells. This turns out to be a $58 million deal. It relates in a major way to a Duke compassionate use or expanded access program (EAP) that already had raised …

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A look at “eyes on the brain organoids” Cell Stem Cell paper

brain organoids eyes

Sometimes a paper really catches your eye like a new Cell Stem Cell pub reporting eye-like structures grown on brain organoids. The paper is Human brain organoids assemble functionally integrated bilateral optic vesicles. Let’s take a quick look at this paper, its context, and the potential big-picture implications. Brain organoids with “eyes”? At first glance, …

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