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Readers’ question: do stem cells for Long COVID make sense including for brain fog?

October 10, 2024 / Professor Paul Knoepfler, Ph.D. / 4 Comments

Do stem cells for Long COVID make sense including for associated brain issues? Two readers of The Niche asked me this question recently. Let’s discuss it. Stem cells for Long COVID worth trying? What is Long COVID? A sizable fraction of people who get COVID-19 never fully recover. They may have symptoms like fatigue, brain […]

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Update on stem cells & cell therapy for COVID trials

July 26, 2023 / Professor Paul Knoepfler, Ph.D. / Leave a Comment

From the beginning of the pandemic, I have been mostly skeptical about the idea of cell therapy for COVID including stem cell therapies. However, at the same time, I’ve closely followed the data, especially up until 2022. Now having just had a nasty bout with COVID myself for the first time this summer, I recently

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Weekly reads: ChatGPT as author, COVID pub concern, CRISPR kit

January 29, 2023 / Professor Paul Knoepfler, Ph.D. / 1 Comment

Have you had the chance to play around on ChatGPT, the open AI? It can “talk” to you in text kind of like a person. I have tried it out. It’s quite interesting to type in scientific questions and see what pops out. Often it is high-quality text and solid ideas, but not always. You

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Weekend reads: WaPo blows it on COVID, paper-mill detector, adult pluripotent stem cells

December 11, 2022 / Professor Paul Knoepfler, Ph.D. / 5 Comments

"Hofstenia miamia, three-banded panther worms. Credit: Mansi Srivastava and Kathleen Mazza-Curll"

Imagine writing or editing an article for the WaPo about risky, unproven medical interventions for COVID that desperate patients might consider. Then you link directly to the websites selling this stuff in your article. What the heck? WaPo links to risky long COVID “treatments” By linking, you not only are driving customers to these firms,

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A close look at new stem cells for COVID trial pub

July 13, 2022 / Professor Paul Knoepfler, Ph.D. / 6 Comments

stem cells for covid 19 kim knoepfler 2021

I’ve been following the stem cells for COVID arena for more than two years. During this time researchers have launched scores of trials. A few have been published including a new one. It’s been a wild ride that at times has included politics and an odd cast of characters. There was Rick Perry and also Rudy Guiliani getting

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Did COVID derail FDA stem cell clinic plan?

June 30, 2022 / Professor Paul Knoepfler, Ph.D. / 2 Comments

The FDA stem cell clinic problem just continues to grow, while the agency has been oddly quiet in this space for more than a year. It’s been a major disappointment, particularly as in recent years FDA leadership had implied that bold action was coming. Their own words spiked expectations that the agency would tackle unproven

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Stem cells for MS & other weekly reads: CRISPR, COVID & a bat cave, Huntington’s

March 6, 2022 / Professor Paul Knoepfler, Ph.D. / 1 Comment

About 1 million people are living with multiple sclerosis in the U.S. alone with millions of other cases around the world so a huge effort has gone into trying to find new approaches to the disease including stem cells for MS. We’ll start our weekly recommended reads by talking about a new paper on MS

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Weekly stem cell reads: COVID kidney, FDA letter, H3.3, EO Wilson

January 2, 2022 / Professor Paul Knoepfler, Ph.D. / Leave a Comment

Happy New Year and get ready for another 364 more days of stem cell excitement and craziness in 2022. In the next day or two I’ll post my predictions for this new year. Recommended reads EO Wilson obit by Carl Zimmer in NYT. Who’s the next EO Wilson or someone like him with such big impact these

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