June 2, 2020

The Niche

Knoepfler lab stem cell blog

Search Results for: john zhang

5 min read

Every year in December and early January I do a post predicting some key events for the stem cell and regenerative medicine field for the upcoming year and today’s post contains my predictions for 2020. You can see my past 2019 predictions along with my grades for them here. I gave myself a B+ for 2019. What grade will I get for 2020? I don’t yet of course, but I often can’t resist making positive predictions even if they are relatively high risk in …Read More

5 min read

What happens next to He Jiankui (贺建奎) or as some people now refer to him, the “CRISPR baby guy”? China has a challenging situation to resolve here, but such conflicts between scientists and governments have happened regularly in history. When scientists go “rogue” (i.e. don’t conform to norms or ethical standards in an extreme way or potentially break laws), governments are often unsure what to do. Also, who decides what’s “rogue”? Where is the line between positive transformative science and something that is really wrong? …Read More

4 min read

The FDA sent a stern letter today to Dr. John Zhang, PhD, MD, the physician who last year created a genetically modified human embryo in the U.S. and then exported it to Mexico where he self-reported creating a genetically modified baby boy. While the genetically modified baby created in Mexico was reportedly seemingly OK, it’s not clear what kind of health issues he might face in the future and I haven’t seen much data on him. I believe his parents subsequently declined to have him participate …Read More

4 min read

By César Palacios-Gonzalez  Earlier this week New Scientist broke the news that the first baby born after Maternal Spindle Transfer is already five months old, and even more, he seems to be doing well. Even when John Zhang’s team has achieved a world first, I agree with Dr. Alison Murdoch in that: “The translation of mitochondrial donation to a clinical procedure is not a race but a goal to be achieved with caution to ensure both safety and reproducibility”. At the moment there is very …Read More

4 min read

Today we got the first report of a baby being born via so-called “3-person IVF”, sometimes called 3-parent IVF, in which the DNA of three people contribute to an offspring. Before discussing this further I have to emphasize that we need proof that this is indeed really a 3-person IVF baby via genetic testing. Until that data is released publicly we should all be cautious on this news. Apparently the clinic plans to present such data later. Assuming it is a 3-person IVF baby, which …Read More

3 min read

Who will be speaking at the upcoming National Academy of Sciences (NAS) meeting on human gene editing? So far we haven’t known, but now we do (if you are eager to find out, skip to bottom of the post). The organizers of the meeting can be found here. Keep in mind that it is probable that some of these organizers, even if not listed below at the bottom of this post, will be present as well. The meeting starts two months from today on December …Read More