Search Results for: somatic cell nuclear transfer

Future of Somatic Cell Nuclear Transfer to make ES Cells

February 1, 2021 / By / 3 Comments
NT-ESC-versus-IPSC

Advances in therapeutic cloning reported in the past year have been very exciting as somatic cell nuclear transfer (SCNT) can be used to produce very powerful human embryonic stem cells (ESC). These new cells are called NT-ESCs for short. Neither embryos nor reprogramming factors are needed to produce human NT-ESCs. See here, here and here for discussions of the pioneering papers reporting creation of …

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Defining epigenetic reprogramming, cellular reprogramming & rejuvenation

September 20, 2023 / By / Leave a Comment
epigenetic reprogramming

Epigenetic reprogramming is a term used in cell biology that is increasingly ending up in news stories too. Unfortunately, some folks, especially in the cellular rejuvenation and anti-aging space, are getting this term and other things confused. Just to start off, epigenetic reprogramming does not specifically mean cellular rejuvenation. The goal of today’s post is …

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What are embryonic stem cells & where do they come from?

April 1, 2023 / By / 3 Comments
Knoepfler lab stem cells

What are embryonic stem cells and how do we scientists obtain them? My lab here at UC Davis School of Medicine has been doing research on embryonic stem cells for more than 14 years. You’ve come to the right place for expert answers on these very intriguing cells. What’s in this article Where do embryonic …

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Stem cell news bites: Astellas trial, cystic fibrosis claim, a few cool papers

February 1, 2021 / By / 5 Comments
Matoba-et-al-Figure-2c-2018

Stem cell news is always burbling up, sometimes right there in front of us on the web and other times via networks of people. Astellas news. Some may remember there used to be this pioneering stem cell biotech called ACT, which then became Ocata, and finally was acquired by the big company Astellas. One of …

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20 Stem Cell Person of The Year 2017 Award Nominees

February 1, 2021 / By / 1 Comment
stem-cell-person-of-the-year

Nominations have closed for the 2017 Stem Cell Person of the Year Award and we have a great group of nominees. I’ve listed them below in alphabetical order, along with a bit of description of who they are, which includes in some cases the language used by the nominator(s). Where possible I’ve included a link …

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GOP reps to Trump: fire NIH Director Collins for stem cell research support

February 1, 2021 / By / 13 Comments
Gallup-Poll-embryonic-stem-cells

Should there be a religious or moral litmus test for the NIH Director? A few dozen super conservative Republican members of Congress have written a letter to President Trump saying he should fire NIH Director Francis Collins. Why? Because they claim that Collins is not conservative enough for their taste and in particular they don’t …

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New Mitalipov paper on stem cell mitochondria: challenge for IPS cell field?

February 1, 2021 / By / 11 Comments
Mitalipov-mitochondrial-mutations

A new paper from Shoukhrat Mitalipov’s lab on stem cell mitochondria points to a pattern whereby induced pluripotent stem (IPS) cells tend to have more problems if they are from older patients. What does this paper mean for the stem cell field and could it impact more specifically the clinical applications of IPS cells? The new …

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