Grading my 20 stem cell & regenerative medicine predictions for 2024

Stem cell, crystal ball, predictions

Did you predict the major events in the stem cell and regenerative medicine field this year? I tried and today’s post are the grades on my predictions. Prediction is a key part of being a scientist even if we may not think about it that much. For instance, we have to try to predict what

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Weekly reads: intermittent fasting and stem cells, vet warning, blastemas

intermittent fasting and stem cells

Intermittent fasting must be good for stem cells, right? It’s not so clear. Like many things in biology, intermittent fasting can have seemingly opposite effects. Before we get into that, the news of the week is that the FDA approved Mesoblast’s Ryoncil MSC drug for some cases of pediatric GvHD. This has sparked lively discussion.

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In landmark, FDA approves first MSC therapy, Mesoblast’s Ryoncil for GvHD

mesoblast ceo dr silvio itescu

In a landmark decision, today the FDA approved Ryoncil from Mesoblast for GvHD. This is the first time the FDA has approved a mescenchymal stromal/stem cell or MSC therapy of any kind. There have been many ups and downs for Mesoblast toward this approval of Ryoncil or remestemcel-L, an allogeneic marrow MSC product. See my

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25 stem cell & regenerative medicine predictions for 2025

regenerative medicine, stem cell predictions

Toward the end of each year I make predictions for the stem cell and regenerative medicine field for the coming year. I’ve been doing this for more than a dozen years in various forms. In this post I’m looking at the (gene-edited, stemness enriched) tea leaves for 2025 for the regenerative arena. These predictions include

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Weekly stem cell reads: HSCT, old embryo models, aging stem cells

stem cell

What is a stem cell therapy? Does it have to include stem cells put into the body? Would you include a therapy that uses differentiated cells made from stem cells? I generally do use the term in that broader way. A similar question comes to mind: what is regenerative medicine? Should it include both cell

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QC Kinetix review: concerns on huge regenerative clinic chain

Tyler Vail, QC Kinetix

QC Kinetix is a relatively new regenerative clinic brand in the U.S. selling unproven cell therapies. I see several specific red flags including a class action lawsuit. They report having 150+ locations, making it potentially the largest chain of unproven clinics in the U.S. Collectively, these clinics could be seeing tens of thousands of customers.

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Refreshing WSJ piece on longevity ‘guru’ David Sinclair

David sinclair, anti-aging

I’ve written before about concerns related to longevity research hype from Harvard professor David Sinclair. The media often eats up statements about longevity from Sinclair and a few other scientists in that space. There is also endless coverage of the latest exploits of wealthy health influencer Bryan Johnson. For that reason it was refreshing to

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Weekly reads: aging cells, scientists relying on ChatGPT, anemone stem cells

cellular aging

Do our aging cells necessitate that we age overall as people? Flipping it around, if we can stop or reverse enough cellular aging, will our overall aging be positively affected? It’s clear that people age very differently from each other and so do our cells and organs. Interestingly, intramurally in a sense the cells and

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