January 27, 2021

The Niche

Trusted stem cell blog & resources

base-editing

4 min read

The paper of the week reports using base-editing, a kind of gene-editing, to reverse mutations associated with rapid aging syndromes, generally called progeria, but there are a lot of other interesting pubs to recommend for reading this week. I go over it all in this post. Gene-editing to fight premature aging syndromes In vivo base editing rescues Hutchinson–Gilford progeria syndrome in mice, Nature. This work comes from a team led by David Liu. It rightly made a big splash in the media. While it’s …Read More