November 26, 2020

The Niche

Knoepfler lab stem cell blog


3 min read

How should we view biohackers and their DIY use of CRISPR outside of the traditional industry or academic lab environment? Introduction to “Biohackers” and DIY CRISPR Who are biohackers exactly? They are people who “hack” their own biology by transforming their bodies through the insertion of technology or modification of their DNA. More rarely, biohackers hack other people’s bodies, but that could change and become more common. In recent years, with the strides made in CRISPR technology, biohacking in genome modification has garnered much …Read More

4 min read

After all this time writing on The Niche here since 2010, I still haven’t entirely resolved certain blogging dilemmas including when a patient discloses something. It’s kind of a jungle out there on the internet. What kinds of tough blogging dilemmas do I face? I’m just going to give you some examples of the more common ones in this post. Patient disclosures & accusations Privacy. One dilemma that still feels like it needs more concrete approaches on my end is when patients publicly disclose things …Read More

2 min read

In this post I list some recent interesting stem cell and science pubs including artificial human embryo research. Engineered human embryo research continues. Scientists for years have been advancing the types of embryo-like structures made from both human and other creature’s cells. In a new Nature Cell Bio pub entitled, “A 3D model of a human epiblast reveals BMP4-driven symmetry breaking”, a team led by Eric Siggia pushed this further. See an image from the paper I’ve included that shows signs of the primitive …Read More

4 min read

For a long time at the end of each year, I’ve been making stem cell predictions for the coming year. Most often I’ve been making a “top 20” list of predictions and today’s post has my list for 2019. You can see how I did for 2018 here, which might have been my best year ever for predictions. We’ll see if I can match that here for 2019. I doubt it. However, I do think my prediction that 2019 will be the worst year …Read More