chimera

Weekly reads: chimera cat vs. chimeric rat, cheap sequencing, more

Venus, cat chimera

When you are a stem cell biologist and especially if you do a blog, you sometimes run across very strange things like a chimera cat. In this case, I stumbled on the whole topic of chimeric cats because I was searching for info on chimeric rats on Google. Of course, I was. It’s kind of […]

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Monkey-pig chimeras pub discouraging for similar human research toward organ transplants

pig-monkey-chimera-that-was-born-but-died

Michael Le Page over at The New Scientist reports on a new paper describing the birth of monkey-piglet chimeras. Unlike most such primate embryo chimeras formed in research in the past, these were allowed to be born. A litter of ten from the new monkey-pig research, two of which were chimeras, all rather quickly died

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Perspectives on pig human chimera paper

human-pig-chimera

A new paper focused on human and other chimeras just came out today in Cell reporting a number of findings, but most strikingly successful generation of human-pig chimeras in utero. The paper, entitled, “Interspecies Chimerism with Mammalian Pluripotent Stem Cells” describes various chimeras including mouse-rat ones, although those have previously been reported. This work comes

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Perspectives on Pedersen Lab Human-Mouse Chimera Paper

human-mouse-chimera

A new Cell Stem Cell paper by Victoria L. Mascetti and Roger Pedersen on human-mouse chimera modeling is quite interesting and important. I really enjoyed this short paper, but I do have a reservation about one way that it is being interpreted. The authors show that human pluripotent stem cells (hPSC) including induced pluripotent stem cells

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NIH suspends funding of human chimera research pending policy review

sn-ratschimera

Chimeras are one of the more controversial and fascinating areas of human stem cell and early embryo research. The notion of a chimera traces back thousands of years to creatures that were mixtures of various animals including humans in some cases. What about a real human chimera embryo? Today, chimera research has the potential to

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