Japan stem cells

Parkinson’s IPS cell trial in Japan switching to allogeneic

Jun-Takahashi

What’s better for stem cell trials such as for vision loss or Parkinson’s Disease: allogeneic or autologous cells? In a major shift earlier this year, the induced pluripotent stem (IPS) cell trial in Japan for treatment of macular degeneration (MD) switched gears from using the patients’ own cells (called “autologous”) to using banked cells from …

Parkinson’s IPS cell trial in Japan switching to allogeneic Read More »

Landmark IPSC clinical study on hold due to genomic issue

IPSC-RPE-sheet

The pioneering induced pluripotent stem cell (IPSC) clinical study in Japan led by top stem cell clinical researcher Dr. Masayo Takahashi has been stopped reports the WSJ in Japan. This development is confirmed by other sources and in a PDF report by RIKEN (in Japanese here). One patient was transplanted in September 2014 with their own IPSC-derived …

Landmark IPSC clinical study on hold due to genomic issue Read More »

Landmark: patient receives first ever iPS cell based transplant

Masayo-Takahashi-150x150

In a major first for the stem cell and regenerative medicine fields, a patient in Japan today received a pioneering transplant of a retinal pigmented epithelial (RPE) sheet made from induced pluripotent stem (iPS) cells, also known by the acronym IPSC. This is the first ever iPS cell-based transplant into a human. The patient is …

Landmark: patient receives first ever iPS cell based transplant Read More »

Don’t Penalize All of RIKEN CDB for STAP Cell Flap

RIKEN-CDB

As the STAP cell fiasco has evolved, there has been discussion of various possible resolutions or even penalties for those involved, both institutions like RIKEN and individuals. One of the most extreme and I believe way out of proportion potential outcomes suggested has been the dismantling of RIKEN’s entire Center for Developmental Biology (CDB) in …

Don’t Penalize All of RIKEN CDB for STAP Cell Flap Read More »

Meet Retina Institute of Japan: translating iPS cells

Retina-Institute-of-Japan

If you are wondering, “How will iPS cells get to help patients?” part of the answer is perhaps the big player and Japanese Institution, Riken and its arm Retina Institute of Japan. The stem cell field is still abuzz about induced pluripotent stem (iPS) cells 7 years after their discovery. This amazing embryonic stem cell-like cells can …

Meet Retina Institute of Japan: translating iPS cells Read More »