September 21, 2020

The Niche

Knoepfler lab stem cell blog

Lung

3 min read

Organoids are providing a novel avenue into the pathogenesis of COVID-19 and novel models for drug screening. A number of new preprints on respiratory organoids shed new light in this area. They were highlighted in a Nature newsy piece, Mini organs reveal how the coronavirus ravages the body. It’s a challenge to study COVID-19 infections because just infecting 2D cultures of various respiratory cells in a dish doesn’t necessarily tell you all you need to know about what goes on in the patient. While 3D organoids aren’t …Read More

5 min read

Washington Post reporters William Wan and Laurie McGinley have a new piece on the unproven regenerative clinic firm the Lung Health Institute. This article has a number of surprises and new insights. Previously the Lung Health Institute was called just the Lung Institute. It was recently acquired by the publicly-traded company H-CYTE, stock symbol HCYT. In the past they marketed stem cells for various pulmonary diseases included COPD. Now it appears they are primarily marketing a form of platelet-rich plasma (PRP), which the company claims in …Read More

4 min read

What’s the deal with lung stem cells and stem cells for lungs? For a long time researchers found that stem cells were elusive in adult lungs. There was debate about whether they even existed, but it now seems fairly established that there are some of the little guys in there. Just because one of the early papers on purported human lung stem cells came from Piero Anversa and has been retracted doesn’t mean these stem cell cells don’t exist at all. Other groups have reported …Read More