October 28, 2020

The Niche

Knoepfler lab stem cell blog

Myc

3 min read

Here are some recommended stem cell and other reads for the week ranging from COVID developments to prosecutors finally catching up with a stem cell surgeon who had many patients die to a list of interesting pubs. Because Trump now has COVID, I wondered on Friday if he might consider trying unproven stem cells or other cellular therapies for the novel coronavirus because so many in his universe seem upbeat about such stuff. Indictment of Paolo Macchiarini From the WaPo, Swedes indict surgeon for …Read More

3 min read

Yamanaka may have found a way to give exogenous Myc the boot from the iPS cell universe. It has always been a frustration in the iPS cell field that Myc, a proto-oncogene, is so important for reprogramming. Yes, you can make iPS cells (especially mouse) without Myc, but it can be orders of magnitude harder, especially when making human iPS cells.  And if you end up with just a little bit too much Myc, the cells can become cancerous. While Myc may not be …Read More