May 28, 2020

The Niche

Knoepfler lab stem cell blog

News

2 min read

365 days a year, 24 hours a day stem cells are growing in labs around the world, providing a never-ending stream of data and products, with real hope, good news, and lots of surprises. You can see some past examples of good news in the stem cell and regenerative medicine field highlighted on The Niche here. Today’s post brings 2 examples of recent good news and a brain organoid surprise. And one bonus more about space and when you’d run out of air (or not …Read More

2 min read

Here are some articles that look especially interesting on stem cells, cancer, and CRISPR. I was just at the SNO meeting in SFO on childhood brain tumors so those are on my mind more. Childhood cerebellar tumours mirror conserved fetal transcriptional programs (Nature) Childhood brain tumors “think” they are building organds in fetuses. H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo. (Acta Neuropathologica) from Suzy Baker-led team. H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and …Read More

2 min read

For more than a dozen years we’ve subscribed to The Sacramento Bee newspaper here in Northern California. During those dozen+ years, newspapers across the U.S. have been under huge financial pressures. At a science level, one of the terrible results of this pressure on newspapers has been the vast number of excellent science writers who have lost their jobs. Our family is starting to wonder if The Sacramento Bee can survive. I’m a big supporter of local papers, but I’m just about to give up …Read More

4 min read

The 60 Minutes show here in the U.S. has done sobering segments over the years on risky, unproven stem cell clinics, but now there is a new episode of 60 Minutes Australia that is the polar opposite: it mostly made a mess of things with its fluffy coverage of the story of a wonderful little girl with cerebral palsy receiving an unproven stem cell transplant at a clinic in Mexico. The new show segment, which you can watch in two parts (see below) on …Read More

1 min read

What’s been up the past week in terms of news in the stem cell world? The Wall Street Journal reports that the New York Stem Cell Foundation (NYSCF) has signed a 20-year lease on a much larger space, in fact twice the current size, in Manhattan. That would seem to be a great sign of things to come for NYSCF, a fantastic organization led by the wonderful Susan Solomon (pictured in her TED talk), who was quoted that the NYSCF team is growing as well. …Read More

1 min read

It’s been a busy few weeks for the stem cell field. Below are some news briefs on developments. RetractionWatch reports that Piero Anversa is leaving Harvard/Brigham and Women’s Hospital after an investigation and dismissed lawsuit he filed against the institution. All still quiet on the STAP cell front at the same institutions. There’s some more clarity and confusion over the Japanese regulatory sphere for IPS cells. New regs may not be issued for another 4 or more months, leaving the clinical studies there in …Read More