Parkinson’s Disease

Weekly reads: Parkinson’s & the gut, sports, cat stem cells

stem cells for Parkinson's, Parkinson's

I’ve met people who are excited about using stem cells for Parkinson’s Disease. Some of these folks have Parkinson’s or are loved ones. Talking to them makes things real. It feel personal and not just scientific. The current treatment options are far away from what is needed for many people. I am optimistic that a […]

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Small positive step for BlueRock Therapeutics Stem Cell Therapy for Parkinson’s

BlueRock Therapeutics, Parkinson's disease, brain imaging

Several groups including Viviane Tabar who is a founding scientist at BlueRock Therapeutics are moving forward on potential cell therapies for Parkinson’s Disease. BlueRock just released some new data that’s worth a look. Check out the new BlueRock poster. In today’s post, I briefly discuss the new data. I also go into the larger context

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Stem cell news & pubs: Parkinson’s, Freezing, COVID, & More

Moll-et-al.-effect-of-freezing-on-stem-cells-stem-cell-news-FI

I find following both stem cell news and the stream of interesting publications to be kind of fun and thought-provoking. This past week or two has been very busy. Here is a news summary and list of notable pubs. Stem Cell News on Parkinson’s Disease There were a number of interesting developments on the Parkinson’s

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IPS cell field update: easy culture, Parkinson’s, scarring, immune cells, & mutations

Fibrosis-model-IPS-cells-Fig-1b-Vijayaraj-et-al-Cell-Reports-2019

Where do things stand today in 2020 with IPS cell research? It’s been 14 years since they were first reported, but they continue to make news. Back in 2006 I was wrapping up my postdoc with Bob Eisenman at The Hutch in Seattle, largely studying Myc, when Shinya Yamanaka published his first induced pluripotent stem

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Stem cells blast into space: Jeanne Loring on the big launch & project specs

NASA-stem-cells-in-space-project-patch

By Jeanne Loring 10, 9, 8, 7, 6, 5, 4, 3, 2, 1 blast off! It’s good to get out of the lab occasionally to get a different perspective.   Last Thursday, December 5, I got a very different perspective, in Cape Canaveral, Florida, where I got to watch the SpaceX Dragon spacecraft be launched by

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Hope on Parkinson’s front: Japan IPSC trial 1st patient

Fig-3i-Kikuchi-et-al.-Nature-2017-IPS-cell-Parkinsons-

In Parkinson’s Disease patients develop neurological dysfunction as they lose a special kind of brain cell called dopaminergic (or dopamine) neurons. While a number of different approaches to this disease have been studied for decades, nothing has proven particularly successful in slowing its progression. As a result there has been a big need for novel thinking

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Lorenz Studer on Day 1 #ISSCR2018: HESC-based therapies for Parkinson’s Disease

GForce_Superhero_logo

One of the highlights of Day 1 of #ISSCR2018 for me so far was the talk by Lorenz Studer (Co-Founder of BlueRock) on the use of human embryonic stem cell (HESC)-derived dopamine neurons for Parkinson’s Disease. Note that for this post and if I have time any others on this meeting, they are probably going

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Ian Wilmut, who cloned Dolly, opens up about his Parkinson’s Disease

Ian-Wilmut

One of the most famous living biological scientists, Sir Ian Wilmut, just announced that he has Parkinson’s Disease. I wish him the best in dealing with this illness. Wilmut is very well-known for having cloned the first mammal, Dolly the Sheep. This work followed on the earlier breakthrough by Sir John Gurdon of cloning the

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On the threshold of cell therapy for Parkinson’s disease

Dopamine-neurons-derived-from-a-Parkinsons-disease-patients-iPSCs-Tyrosine-hydroxylase-1

By Jeanne Loring There are ten million people in the world who have Parkinson’s disease. 125,000 of these are living in California.  People with the disease often have to step away from their jobs because the main symptoms – tremor or freezing up of muscles – make it difficult to get through a whole day

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