Research

Stem cell research.

Weekly reads: woolly mice & pseudo-mammoths, eye repair good news, Mesoblast $1.5M price tag

woolly mice

Ever heard of woolly mice? I hadn’t either until recently. The story begins with de-extinction research. De-extinction can be both cool and arguably a colossal waste of research dollars. The specific effort to de-extinct woolly mammoths fits that dual classification. Woolly mice on the road back to mammoths? Let’s dig into this with some news: […]

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Weekly reads: CBER changes, Parkinson’s, 2-dad mice, NIH woes continue

dr. peter marks, cell therapy

I recently looked at the organizational chart at the FDA’s Center for Biologics Evaluation and Research or CBER. Why? I have been anticipating some possible big changes there with the new administration. After all, with HHS Secretary RFK Jr. having previously claimed that the FDA was suppressing various unproven things including at least two kinds

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Grading my 20 stem cell & regenerative medicine predictions for 2024

Stem cell, crystal ball, predictions

Did you predict the major events in the stem cell and regenerative medicine field this year? I tried and today’s post are the grades on my predictions. Prediction is a key part of being a scientist even if we may not think about it that much. For instance, we have to try to predict what

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Weekly reads: intermittent fasting and stem cells, vet warning, blastemas

intermittent fasting and stem cells

Intermittent fasting must be good for stem cells, right? It’s not so clear. Like many things in biology, intermittent fasting can have seemingly opposite effects. Before we get into that, the news of the week is that the FDA approved Mesoblast’s Ryoncil MSC drug for some cases of pediatric GvHD. This has sparked lively discussion.

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Weekly reads: aging cells, scientists relying on ChatGPT, anemone stem cells

cellular aging

Do our aging cells necessitate that we age overall as people? Flipping it around, if we can stop or reverse enough cellular aging, will our overall aging be positively affected? It’s clear that people age very differently from each other and so do our cells and organs. Interestingly, intramurally in a sense the cells and

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Unapologetic He Jiankui eager for more human germline gene editing with help from tech bros

He Jiankui lab, He Jiankui

For a few years, biophysicist He Jiankui might have been one of the most recognizable scientists on the planet. He made three “CRISPR babies” or gene edited people. However, his gene editing went badly and as best as we can tell his efforts did not result in precision edits. It’s unclear if he had institutional

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ISCT launches new resource on unproven cell & gene therapies

ISCT, ISCT guide

The International Society for Cell & Gene Therapy or ISCT is a great organization in our field. They have launched a new guide to help healthcare providers navigate this complex area. Click on the image below to check it out. This new resource is important because healthcare providers, researchers, and the public need authoritative information.

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Recommended reads: gov scientists fear Trump 2nd term, MYCT1 in HSCs, in vivo editing

Trump

I’ve only met one scientist who was openly a Trump fan, but I’m sure there are more out there. Still, it seems most scientists are no fans of the former president. A new WaPo piece highlights how federal scientists are worrying about a possible second term for the former president. Government scientists & a second

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