Research

Stem cell research.

Weekly reads & stem cell news: New York axes NYSTEM, fetal tissue rules reversed, pubs & more

stem cell book

It’s been a week with a wide variety of regenerative medicine papers and stem cell news. Here’s my earlier take from a few days ago on the Belmonte-led human-monkey chimeric embryo paper in Cell that broke this week. A few days ago I also put up a new video on our Stem Cell YouTube Channel …

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FDA warns Joseph Mercola on COVID-19 claims

joseph mercola and unproven stem cells

Those of you following the arena of unproven stem cells might recognize the name Dr. Joseph Mercola. He’s a promoter of alternative medicine. Over the years his name has also popped related to the marketing of unproven stem cell offerings in various ways. Now the FDA has warned Joseph Mercola on what it says are unapproved …

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What are induced pluripotent stem cells or IPS cells & clinical prospects?

induced pluripotent stem cells clinical trials map

Induced pluripotent stem cells or IPS cells just might be the most exciting development in the stem cell field over the last 15 years. They have unique potential for clinical impact for regenerative medicine too, both through their use to produce differentiated cellular therapies and indirectly via disease modeling as well as drug screening. The …

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Recommended reads: Single-cell work, COVID twin study, more

single cell analysis neural stem cells

Sometimes it seems like a theme spontaneously emerges in pubs that I want to read for a given week like the set of single-cell analysis papers but there are diverse, other items including a striking day-night brain stem cell cycle paper and an interesting piece on identical twins who got COVID. What are you reading …

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2020 The Screamers Science Hype Award goes to Stephen Hahn

Dr-Stephen-Hahn-Commissioner-of-FDA

Today’s post announces the winner of the 2020 The Screamers Science Hype Award. Since this is the inaugural year for The Screamers, I’m just going to give out one main award: Overall Worst Science Hype. Science Hype Award to FDA Commissioner Stephen Hahn Remarkably, the winner of the overall The Screamers Award for Science Hype …

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21 Stem Cell Research & Regenerative Medicine 2021 Predictions

stem-cell-crystal-ball-300x3001

In any given field of biomedical science like stem cell research and regenerative medicine, it’s very useful if you can accurately predict the future. It seems, though, that predictions are far more difficult within the more exciting and rapidly-changing fields. The field of stem cells and regenerative medicine fits that bill. Past stem cell research …

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Small umbilical cord stem cell COVID-19 trial: sign of efficacy?

Cord-blood-autism

A new paper today in Stem Cells Translational Medicine on a small COVID-19 Phase 1/2a trial using an umbilical cord stem cell product reports a surprising degree of possible efficacy. What’s the scoop here and could there be some hype in the media about this new study such as one of the authors describing the …

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Recommended reads: MSCs, vision, endothelial cells, more

wang et al 2020 science advances

What a year 2020 was, but there was still plenty of great science, which continues now in 2021 including published research like today’s recommended pieces and there’s one thread on MSCs today. The Niche new look, more features, and a Medical Advisory Board for 2021 Before we get to the recommended reads, note that 2021 …

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Spicy stem cell pathways & other recommended reads

Nociceptor-mediated HSC mobilization. "Schematic representation showing that nociceptive-nerve-derived CGRP, but not substance P, acts via CGRP receptors on HSCs to enhance their mobilization via a cAMP-mediated signalling pathway. "Gao et al Nature, Capsaicin acts via nociceptor signaling to mobilize blood stem cells.

The stem cell paper of the week is a fun one about how capsaicin and nociceptors reportedly mobilize blood stem cells.  However, since the authors only show this in mice, could it also happen in humans? They argue it’s likely happening in people too. Note that nociceptors are special structures in our bodies that sense …

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