Weekly Reads

The Niche’s recommended Weekly Reads on stem cell research and regenerative medicine.

Weekly reads: 2nd death from Sarepta’s Elevidys, more on Verdun’s firing, ESC autism models, new human-mouse chimeras, Lilly buys Verve

Sarepta, Elevidys

After the good news of Friday that a stem cells for type 1 diabetes therapy appears to be effective in a small trial, we should also note that a second teenager has died after receiving Sarepta’s Elevidys gene therapy for Duchenne muscular dystrophy. The cause of death again was liver failure. Sarepta has limited shipments […]

Weekly reads: 2nd death from Sarepta’s Elevidys, more on Verdun’s firing, ESC autism models, new human-mouse chimeras, Lilly buys Verve Read More »

Weekly reads: more hype on dire wolves, stemy coin crypto fraud, FDA to rely on AI, vascular organoids

Fake de-extinction, dire wolves

Despite intense criticism, Colossal Biosciences continues to claim de-extinction of dire wolves. The false claims and hype are such a big mistake. It’s not even necessary either. The firm has a strong scientist in its scientific leader Beth Shapiro. It has George Church. To Colossal, I say that your firm should just say what it

Weekly reads: more hype on dire wolves, stemy coin crypto fraud, FDA to rely on AI, vascular organoids Read More »

Weekly reads: cell and gene therapy deregulation, axed grant database, H3.3 in mESCs, remembering James Till

RFK Jr., cell and gene therapy

It’s been a crazy week on the cell and gene therapy front. We live in strange times more generally. I just wrote about a Thursday FDA cell and gene therapy roundtable that generally promoted the idea of less oversight. And far more speed to human use. RFK Jr. was present at the end and spoke.

Weekly reads: cell and gene therapy deregulation, axed grant database, H3.3 in mESCs, remembering James Till Read More »

Weekly reads: longevity news on Retro & Altos Labs, free Harvard stem cell course, cord blood

senolytics, senolytic drugs

Longevity research is a growing part of the overall regenerative medicine field. Rewinding, when I first started blogging here on The Niche in 2010, longevity was more of a fringe field. In just 15 years, it has become a generally legit area, even if one often filled with hype. It has its share of scammers

Weekly reads: longevity news on Retro & Altos Labs, free Harvard stem cell course, cord blood Read More »

Weekly reads: custom CRISPR therapy for baby, stem cells make amniotic sacs, 2 anti-aging influencer tweets, Nurown

CRISPR therapy, gene editing baby

There has been a sizable downturn for the CRISPR therapy biotech arena. Firms like Editas, Verve, Intellia, and even CRISPR Therapeutics, which has garnered an FDA approval, have had struggles recently. It feels like a disconnect here in a way because overall gene editing and gene therapy have never seemed more promising. But being a

Weekly reads: custom CRISPR therapy for baby, stem cells make amniotic sacs, 2 anti-aging influencer tweets, Nurown Read More »

Weekly reads: upbeat early Aspen stem cells for Parkinson’s trial data, Capricor, hematopoietic editing

Autologous iPSC-derived neurons, stem cells for Parkinson's

I recently wrote about the upbeat early reports from two allogeneic trials of stem cells for Parkinson’s. Now there’s additional encouraging early news on this front but using patients’ own cells. This is one of the most promising areas of regenerative medicine. Stem cells for Parkinson’s: Aspen Neuroscience upbeat early data California biotech Aspen Neuroscience

Weekly reads: upbeat early Aspen stem cells for Parkinson’s trial data, Capricor, hematopoietic editing Read More »

Weekly reads: stem cells everywhere, MSCs for MS?, nanostickers, Makary update

MSC cruises, MSCs for MS

It was another crazy week for me with tons of grant work, but news  and research in the regenerative medicine world keep on popping up including a paper on MSCs for MS. I’ve realized that even when I’m trying to take a short break, I often see science and signs of stem cells popping up

Weekly reads: stem cells everywhere, MSCs for MS?, nanostickers, Makary update Read More »

Weekly reads: stem cell marathon, Ray Therapeutics, stem cells making you fat?

marathon, stem cell

Stem cells can be serious business, but sometimes stories come along that are just fun like a lady running a marathon dressed as a stem cell. How cool is this: “Louise Cato from Somerset is doing the run to raise money for the charity Anthony Nolan, after her dad had a bone marrow transplant over

Weekly reads: stem cell marathon, Ray Therapeutics, stem cells making you fat? Read More »

Weekly stem cell reads: tomato stem cells, FDA blacklist, CALEC, odd RFK Jr. summit

stem cell, tomato stem cells

Some of you may know that gardening is one of my hobbies and I see it as akin to science, even like growing stem cell cultures. Tomatoes are my favorite thing to grow. About ten years ago I started sprouting my own tomato plants from seed. It’s surprisingly easy with grow lights. This way you

Weekly stem cell reads: tomato stem cells, FDA blacklist, CALEC, odd RFK Jr. summit Read More »

Weekly reads: robot scientist, stem cell sperm make a baby, assembloids & sense

How about a robot grant writing scientist?

What’s life as an academic scientist really like now? It’s gotten worse in the U.S. recently. There’s more stress about funding including on levels that we can’t control. I’m writing too many grant proposals these days. I’m wondering how much researchers are now using AI for grant writing, which I have not done. Does AI

Weekly reads: robot scientist, stem cell sperm make a baby, assembloids & sense Read More »

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