Search Results for: ES cell

A reality check on the radiation spreading across the globe

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  The tragic 9.0 earthquake and tsunamis that hit Japan a few weeks ago are having lasting consequences not only for Japan, but also for the world via radiation. One area of particular concern is the radiation that has leaked and is continuing to leak from the damaged nuclear reactors. At this point, the radiation …

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Science is a national security issue

Reportedly,  House Republicans are proposing a continuing resolution (CR) to fund the rest of FY2011 at 2008 funding levels.  To achieve such an end, the Republicans would have to invoke serious cuts through the federal budget. Not only would such cuts likely damage the U.S. economy, but also they would have major other negative consequences. …

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My Cancer: how I became an advocate too

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There is a kind of invisible cultural wall between patients such as cancer patients and biomedical scientists like me, but this wall does not have to exist and indeed it is a negative wall as patients, scientists, doctors, agencies, and advocates can achieve far more together than apart. But the wall is surprisingly strong. Last …

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Huntington’s Disease, a major new finding

Huntingtons-Disease

This is the first post in a series focusing on stem cell advances related to specific diseases. Today we discuss Huntington’s Disease and a paper that came out yesterday in the journal Neuron that provides some significant insight into the mechanisms behind the disease. It is entitled: Huntingtin Is Required for Mitotic Spindle Orientation and …

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I Hate Your Paper: Dr. No and the Editors that are ruining peer review

Dr.-No-peer-review

Update: Now in 2020 it seems that peer review remains very problematic. The Scientist has a few pieces out on the trouble with peer review including my personal favorite: I Hate Your Paper. That article rings so true as do the quotes from the scientists. Peer review in the stem cell field and the IPS cell …

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Tumorigenicity and Pluripotency teased apart? Not yet for Myc

Fig.-5-Nakagawa-et-al.-Myc-in-cancer-and-IPScs

A paper just came out in PNAS entitled “Promotion of direct reprogramming by transformation-deficient Myc“. The main thrust of this paper is that the tumorigenic and pluripotency-related functions of Myc could be separated. It focused primarily on the lesser studied LMyc. The topic of the intertwined good (pluripotency) and bad (tumorigenicity) functions of Myc, addressed …

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