November 26, 2020

The Niche

Knoepfler lab stem cell blog

2 min read

It’s fitting, given the edginess over the election, that Halloween is falling only a few days before election day so here is a list of recommended stem cell reads for you to dive into some biomedical science. Liver buds from stem cells Generation of human induced pluripotent stem cell-derived liver buds with chemically defined and animal origin-free media, Scientific Reports. In a decade might we have liver transplants based on this technology? If so, it will probably be small structures that are like a …Read More

1 min read

Some scientists, even on Halloween, might be relatively immune to the fear of things that nonetheless freak out many everyday normal people. Brains, powerful lasers, antibiotic resistant genetically-modified bacteria, potent viruses, radioactivity. The list goes on and on. Mutant cells and animals. DNA containing cancer-causing genes. So as Halloween approaches, what does scare the heck out of scientists? Here is my list of the top scariest Halloween costumes to freak the lab coats off of scientists. If you are a scientist you might want to …Read More

6 min read

Last week I wrote a long post detailing the troubling multimillion-dollar reverberations between the Duke autism program and a for-profit stem cell clinic in Panama called The Stem Cell Institute. The potential entanglements between the Duke group and the Panama clinic raise a bunch of questions and concerns. They center on questionable, unproven autism “treatments”. In Duke’s case, their own clinical trial showed there was no benefit, but they forging ahead anyway. Muddy waters This Duke-stem cell clinic situation is a prime example of …Read More

7 min read

IPS cell research is a growing area of promise for regenerative medicine. These stem cells, also known as iPSCs or more formally as Induced Pluripotent Stem Cells, are engineered cells that are programmed to function the same way as embryonic stem cells. They can be differentiated into possibly any type of cell that is needed for therapeutic purposes. Since iPSC production was first reported by Shinya Yamanaka using mouse and human cells in 2006 and 2007, respectively, cells from a whole host of species have …Read More