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Weekly reads: AL embryos ruling, blasting cancer, marrow organoids, beef inside rice plants

Multipotent & totipotent vs pluripotent stem cells, very early human embryos totipotent stem cells

Are small clusters of cells that make up 5-day-old human embryos equivalent to children? Biologically and in terms of just common sense, the answer is “no.” These tiny spheres have around 100 cells and no organs. Actual people have many trillions of cells, brains, and other organs. Alabama law on embryos may block IVF About …

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Weekly reads: big Retraction Watch news, stem cells & metastasis, an FDA approval, Iowa AG sues clinic

Retraction watch

Retraction Watch has been a great resource for those of us who have been following research misconduct. They widely cover and conduct research on retractions, corrections, and other developments in this space. Unfortunately, there’s been plenty to write about even just within the stem cell and cell therapy arena, which is my primary interest. Think …

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Weekly reads: Conception Bio & IVG, MYC, Stanford Prez resigns

Conception Bio, IVG

The Bay Area biotech Conception Bio has an intriguing name. What does “conception” mean here? Scientists can make many things from stem cells. For example, lately I’ve written a lot about stem cell-based human embryo models. Another intriguing area is called in vitro gametogenesis or IVG, where Conception Bio is a leader. IVG means making …

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He Jiankui proposes editing human embryos again

He Jiankui

It wasn’t that long ago that Chinese scientist He Jiankui got out of jail. Why was he in there? For doing unauthorized human CRISPR to make heritably gene-edited humans. He botched that and apparently forged some approvals to make it happen. The three children involved may have life-long health problems as a result. I wrote …

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Stem cell therapy cost in 2024: data & analysis

stem cell therapy cost

How much does stem cell therapy cost in 2024? How have prices changed? To authoritatively answer these questions now we need data from the present and past along with expert perspectives. Some surprises come up in this new analysis. In this article Intro  | Stem Cell Therapy Cost: $10,000-$20,000 | Why do stem cells cost so much? …

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Weekly reads: gene therapy nod, Nature pub ethics, CRISPR LDL

Multipotent & totipotent vs pluripotent stem cells, very early human embryos totipotent stem cells

Totipotency literally means all powerful, but it refers in biology to specific cells. These cells can make every type of cell in the body of an organism plus the extraembryonic tissues needed for development. This includes humans. So if you could reprogram human cells like blood or skin cells into totipotent stem cells, you might …

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Questions on National Academies in vitro gametogenesis (IVG) meeting sponsorship

in vitro gametogenesis, IVG

Research on in vitro gametogenesis or IVG is jumping ahead and such work could one day lead to new infertility treatments. In vitro gametogenesis is the process of producing gametes (sperm and eggs) from stem cells. Those powerful stem cells, called iPS cells, can be made from ordinary adult cells like skin or blood cells. …

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Weekly reads: FDA nod on new cell therapy, gray hair, pong-playing cells

It’s a big challenge to get a cell therapy approved by the FDA and if you look at my list of FDA-approved stem cell therapies, it’s not as long as we might hope. FDA OK on cell therapy from Gamida Cell For this reason, it was excellent news to see that the FDA approved a …

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Stem cell research ethics topics: organoid consciousness & embryo models

brain organoids sm

Someday could human brain organoids get to the point of having organized human-like thoughts? Even consciousness? The more time passes, the less likely I think this is. It’s not impossible, but brain organoids have big limitations in that regard. To be clear, I don’t mean brain organoids having some vaguely human brain-like electrical activity. Even monolayers of …

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