Search Results for: parkinson's

Parkinson’s Disease, promising new results on iPS cells

Parkinsons-Disease-stem-cells

UPDATE: A second recent study, this one in Nature Genetics has found a novel genetic link between the immune system and Parkinson’s Disease. The authors were screening for genomic variants unique to Parkinson’s patients, finding known ones but also a novel linkage. The link was with the HLA region, known to play a key role […]

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Recommended reads: MSC analysis points to challenges, IPSC NKs kill liver cancer, turning white fat into brown

MSC single cell transcriptome, MSC

Mesenchymal stromal/stem cells or MSCs are widely used by unproven clinics, but MSC research also suggests real promise in specific areas. Clinics mainly use adipose MSCs (often called SVF) or bone marrow MSCs. However, umbilical cord MSC preparations are getting more popular too. Many questions swirl around the use of MSCs including what exactly are

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Recommend reads: FDA SVF warning, big Aspen grant, CSI finale invokes stem cells

SVF

One of the most contentious areas in the regenerative medicine arena is whether a fat tissue product called stromal vascular fraction or SVF is a drug. The FDA says SVF, even in autologous form, is a drug. It is seeking an injunction against a California-based network of SVF clinics but lost the initial case. That

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Recent stem cell & regenerative medicine good news

stem cell good news, good news

Looking for some stem cell good news? You’ll like today’s post. One mission of this blog The Niche is to promote rigorous science-based regenerative medicine, which can lead to investigating and writing about not-so-upbeat stuff. Risky clinics. People getting hurt. Patient lawsuits. Serious FDA, FTC, or state AG regulatory developments. Such actions can be good

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Key Mayo Clinic stem cell webpage is overexuberant & outdated

The Mayo Clinic.

The Mayo Clinic does some great research on stem cells and regenerative medicine. However, at times I’ve felt that a few Mayo researchers are overexuberant. This mainly relates to certain not-yet-proven stem cell and related offerings. Fitting with that perception, the Mayo website also has some inaccurate stem cell content that leans toward overstating things.

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Weekly reads: game of clones, super-SOX, Moonwalk Bio, Great Wall’s living skin

dog clones

I’m trying to remember the first time I ever heard about clones. It had to be as a kid. Maybe in a monster movie or TV show? Possibly a clone was referred to by the more general term “double”, which is not necessarily a clone. Whatever it was, I’m sure as a kid that I

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20 stem cell & regenerative medicine predictions for 2024

Stem cell, crystal ball, predictions

Each year I make predictions for the stem cell and regenerative medicine field for the following year. Today’s prediction post is focused on what to expect in 2024. You can also see my stem cell predictions for 2023 and my grades on how I did. I also have made a video version of these predictions so please

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Weekly reads: stem cells for MS, good news x2, extending dog years, Neuralink updates

stem cells for MS

For about as long as I’ve been writing The Niche, people have been asking about stem cells for MS. There’s a huge need for new therapies. While a chemo-based approach with autologous hematopoietic stem cell transplantation (HSCT) looks to work for certain cases of multiple sclerosis (although not yet approved in the US), other cell

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Man reportedly dies after getting unproven stem cell therapy in Mexico

stem cell death, stem cell therapy in mexico

A surfer news site reported that a man recently died after getting an unproven stem cell therapy in Mexico. The article is entitled Tragedy strikes in Mexico as Shane Dorian’s traveling companion for “life-altering” stem-cell therapy dies. Shane Dorian is a famous surfer who hopes to fight aging at 51. As part of that effort, Dorian

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