Earlier this week I posted an interview with Steven Pinker on CRISPR, human germline modification, and bioethics. With only a few exceptions, I strongly disagree with Pinker’s philosophy in these areas and I knew going into the interview that his answers would likely go against my own views. I also expected the interview would anger …
Why interview Steven Pinker on my blog if I strongly disagree with him? Read More »
What is the “proper” amount of freedom of choice for patients in medicine? What if the treatments in question are experimental and come with their own baggage of associated risks, personal costs, and potential costs to society? More broadly, do patients have a fundamental right to medical choice? These questions seem particularly appropriate today on …
Controversial TV physician Dr. Mehmet Oz hasn’t had a great year what with his disastrous testimony before Congress. (2020 Update; Dr. Oz recently had a good show on stem cell clinics so that’s something. I discussed issues with his staff prior to the show.) Now Dr. Oz has been slammed by a group doctors from …
Doctors call for Dr. Oz to be booted from Columbia Read More »
In the last few months the FDA has taken steps toward crystalizing regulatory oversight of stem cell and more broadly cell and tissue-based therapies. These steps come in the form of several draft guidances (see here, here, and here) . The Alliance for Regenerative Medicine (ARM) has responded to the draft guidance on Minimal Manipulation. For example, ARM has …
ARM Asks FDA for Clarification on Draft Guidance on Minimal Manipulation Read More »
It’s hard to even imagine the world of investigative medicine without the wonderful resource of Clinicaltrials.gov, the global hub for clinical trial listings. I recently interviewed the Director of Clinicaltrials.gov, Dr. Deborah Zarin here, which is a fascinating read. As great as Clinicaltrials.gov is as a resource, unfortunately it faces a new, rapidly growing problem that is a serious …
Clinicaltrials.gov Mission At Risk From Proliferating For-Profit Trials Read More »
Stem cell-based Regenerative Medicine has huge power for good in the clinic and at the same time great potential for economic development. Those two things go hand in hand. As I argued in my stem cell book, biotech commercialization of stem cells is not a bad thing, but rather if it is done responsibly it …
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Should a company be able to have a gene patent and more generally and practically speaking can genes be patented? Patent and IP issues always raise a myriad of questions so what about a patent case on a company called Myriad? Complicated, right? If genes in their natural form cannot be patented, does that mean …
Myriad SCOTUS Decision: Can you have a gene patent? Read More »
One of the great areas of confusion over the human cloning development this week is whether human cloning is legal or illegal. With few exceptions, human cloning in general is legal in the US. Update: in 2020 it still appears that reproductive human cloning is legal in the US. It just hasn’t gotten that much …
Deja you: human cloning generally legal in the US Read More »
More and more evidence is accumulating that the alleged iPS cell transplantation in human patients by Dr. Hisashi Moriguchi was bunk. Nature today has a piece out today on the story providing more quotes about the case that suggest the whole thing was made up. Rather than re-hash all the details, in this post I’m going …
The Moriguchi iPS transplant fable: key lessons & where do we go from here Read More »