More CRISPR’d human embryos, but this time in America? MIT Tech Review is reporting that Oregon scientist Shoukhrat Mitalipov has used CRISPR on human embryos in his lab in the US. Apparently a paper is in the works on this. While details are sketchy and some specifics remain to be clarified to be sure of […]
In first for U.S., Mitalipov reportedly CRISPR’d human embryos & it was great Read More »
2,000 is a big number. As of this week I’ve now published 2,000 posts here on The Niche since I started back in early 2010. I can’t quite believe it myself. To celebrate that milestone, I have revamped The Niche in terms of its organization and style with the help of a very skilled web
The Niche’s 2,000th post: where do we go from here? Read More »
By Cátia Bandeiras, PhD Student at University of Lisbon, Portugal and Massachusetts Institute of Technology. See tweets from the conference using #ISSCR2017 @apulgarita I just wrapped up my stay at the Annual Meeting of ISSCR 2017, which happened in Boston. I decided to take advantage of the fact that I am living in Boston at
Hunting for computational approaches for stem cells at ISSCR2017 Read More »
A new, brief study in mice from the Vinit Mahajan lab argues CRISPR can have very large numbers of off-target sites. Their paper is entitled “Unexpected mutations after CRISPR–Cas9 editing in vivo” and was published in Nature Methods.This work has garnered a lot of attention in the media. Let’s take a journal club review kind of approach
Journal club review of new CRISPR ‘lots of off-target activity’ mouse paper Read More »
Cut, modify, paste… It’s kind of a CRISPR mantra for those of us using gene editing in the lab. But it’s supposed to be happening just on DNA, right? Now it appears that someone on a team of human embryo CRISPR researchers possibly got carried away with the cutting-modifying-pasting mindset to take it beyond DNA to also do
Human embryo CRISPR pub includes plagiarism: the victim’s unique account Read More »
The first report of the use of CRISPR gene editing in normal human embryos was published today as a short paper from a team in China. There have been rumors for over a year that more CRISPR human embryo papers were coming including some using normal embryos. Here’s one and we can now expect more even
Paper on 1st use of CRISPR in normal human embryos: problems remain Read More »
The Future of Genomic Medicine conference last week down in La Jolla at Scripps was one of my favorite meetings ever. I wish I had time to have live blogged it more beyond the one post I did about some gene editing talks. Below I discuss 10 top takeaways from this great meeting that I’m planning to attend
10 takeaways from Future of Genomic Medicine meeting Read More »
What is the future of Genome Medicine? The meeting by that same name that I’m at down here in La Jolla is all about tackling this question and the line up of speakers today on the first day is amazing. I’m speaking about IPS cells as a basis for personalized medicine tomorrow morning so that’s exciting.
Live blogging Future of Genome Medicine: great talks by Feng Zhang & others Read More »
So everyone is buzzing about the CRISPR patent court decision (which BTW I think was flawed but that’s for another post), but the research roars on at warp speed. Here are 7 recent CRISPR articles that caught my attention. What are your favorite recent CRISPR papers? Genome surgery using Cas9 ribonucleoproteins for the treatment of
7 cool recent CRISPR articles Read More »
What are the latest developments in stem cells and regenerative medicine in this first week of 2017 and right before the end of the past year? Here are some of the headlines and papers that have popped up that seem notable or surprising. Be sure to also check out our stem cell & regenerative medicine
TGIF: Week’s Stem Cell Headlines, Papers, & Resources Read More »