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A look at “eyes on the brain organoids” Cell Stem Cell paper

August 17, 2021 / Professor Paul Knoepfler, Ph.D. / 2 Comments

Sometimes a paper really catches your eye like a new Cell Stem Cell pub reporting eye-like structures grown on brain organoids. The paper is Human brain organoids assemble functionally integrated bilateral optic vesicles. Let’s take a quick look at this paper, its context, and the potential big-picture implications. Brain organoids with “eyes”? At first glance, […]

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Weekly reads including MSCs & cancer stem cells

August 8, 2021 / Professor Paul Knoepfler, Ph.D. / Leave a Comment

One of my main interests is the relationship between stem cells and cancer as well as what makes cancer stem cells tick. This week I’ve chosen to highlight articles on the role of stem cells in cancer plus other interesting publications. Cancer pubs related to stem cells including on cancer stem cells Identification of cancer-related

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Stem cell Alzheimer’s disease research

July 13, 2021 / Mina Kim / Leave a Comment

Alzheimers disease, Alzheimers disease stem cell

Could stem cell Alzheimer’s Disease (AD) research provide a potential path to future treatment or preventative measures? The goal of today’s post is to provide a review of the state of the field in this area including possible approaches and challenges. You can watch a video covering the topic by Dr. Paul Knoepfler below on

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What are adult stem cells & their clinical applications?

June 16, 2021 / Professor Paul Knoepfler, Ph.D. / 2 Comments

When someone uses the term “adult stem cells” you might think that simply means stem cells from adults. However, it’s not that simple. The goal of today’s post is to help you get all the key facts about adult stem cells. This includes the different types of adult stem cells and their clinical potential. What

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Weekly reads: cancer stem cells & other pubs plus a puzzler

June 6, 2021 / Professor Paul Knoepfler, Ph.D. / 4 Comments

Cancer stem cells are one of the most interesting areas of research, intersecting the stem cell and cancer fields. Today’s weekly reads post highlights some new cancer stem cell articles along with some other interesting papers. I also note a recent weak stem cell clinical trial paper that is not a recommended read but is

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The Niche stem cell picture contest winners: gut & astrocytes

May 5, 2021 / Professor Paul Knoepfler, Ph.D. / 1 Comment

I got some great entries for our The Niche stem cell picture contest. While I expected many bright colorful images, every year some of the pictures surprise me in certain ways. There was another surprise in that two entrants in the contest, both Assistant Professors, are sisters. A talented family! You can see the previous

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Weekly reads & stem cell news: New York axes NYSTEM, fetal tissue rules reversed, pubs & more

April 18, 2021 / Professor Paul Knoepfler, Ph.D. / Leave a Comment

It’s been a week with a wide variety of regenerative medicine papers and stem cell news. Here’s my earlier take from a few days ago on the Belmonte-led human-monkey chimeric embryo paper in Cell that broke this week. A few days ago I also put up a new video on our Stem Cell YouTube Channel

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Multipotent and totipotent vs pluripotent stem cells

March 16, 2021 / Professor Paul Knoepfler, Ph.D. / 3 Comments

Multipotent & totipotent vs pluripotent stem cells, very early human embryos totipotent stem cells

What’s the difference between multipotent stem cells, totipotent stem cells, and pluripotent stem cells? The goal of today’s post is to help you learn and be clear on the differences. What’s in this article Definition of stem cells |Totipotent vs pluripotent stem cells | Pluripotent stem cells | Multipotent stem cells | The best kind of stem

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Lawmaker indicted for selling fake stem cells for COVID & more

February 4, 2021 / Professor Paul Knoepfler, Ph.D. / 1 Comment

patricia derges indictment for fake stem cells sm

A grand jury indicted Missouri state representative and assistant physician Patricia Derges for allegedly selling and injecting patients with fake stem cells. The injection was reportedly just of amniotic fluid, but Derges allegedly claimed it was a stem cell treatment. NBC News was one of several media outlets that broke the story here after the

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