Search Results for: embryonic stem cells

What are induced pluripotent stem cells or IPS cells?

induced pluripotent stem cells clinical trials map

Induced pluripotent stem cells or iPS cells just might be the most exciting development in the stem cell field over the last 15 years. They have unique potential for clinical impact for regenerative medicine too. This may manifest both through their use to produce differentiated cellular therapies and indirectly via disease modeling as well as […]

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Spicy stem cell pathways & other recommended reads

Nociceptor-mediated HSC mobilization. "Schematic representation showing that nociceptive-nerve-derived CGRP, but not substance P, acts via CGRP receptors on HSCs to enhance their mobilization via a cAMP-mediated signalling pathway. "Gao et al Nature, Capsaicin acts via nociceptor signaling to mobilize blood stem cells.

The stem cell paper of the week is a fun one about how capsaicin and nociceptors reportedly mobilize blood stem cells.  However, since the authors only show this in mice, could it also happen in humans? They argue it’s likely happening in people too. Note that nociceptors are special structures in our bodies that sense

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What are totipotent stem cells & what can they do?

Multipotent & totipotent vs pluripotent stem cells, very early human embryos totipotent stem cells

Sometimes patients or my students ask me, “What are the best stem cells?” what information are they looking for? I think they often are looking for the most powerful stem cells so perhaps they should be asking, “What are totipotent stem cells?” Other times it seems what patients specifically want to know is what might

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Stem cell reads: liver buds, MSCs, SMARC, more

Liver-buds-from-stem-cells

It’s fitting, given the edginess over the election, that Halloween is falling only a few days before election day so here is a list of recommended stem cell reads for you to dive into some biomedical science. Liver buds from stem cells Generation of human induced pluripotent stem cell-derived liver buds with chemically defined and

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Trump, GOP hypocrisy on Regeneron COVID-19 fetal, stem cell work

293T-HEK-cells-Trump-fetal-stem-cells-sm

Are Trump and the Republican Party showing major hypocrisy over Trump’s use of experimental COVID-19 therapies in part developed by Regeneron using embryonic and fetal cells? The Internet is kind of blowing up over this. Trump’s collision with stem cells For example, people are directly confronting Trump on Twitter over his recent all caps tweet

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Recommended reads: FDA warning, COVID updates, stem cell pubs

Tao-et-al-Stem-Cell-Reports-2020-Fig.-1c-small

What’s been going on in the stem cell and regenerative medicine field over the past week and what are some worthwhile things to read? Today’s post has recommended recent reads from the scientific literature and the media. I’ve also got our weekly stem cell/regenerative medicine quiz question and the answer to last week’s. You can

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Recommended reads: COVID-19 updates, FDA stem cell nod, PRC2, more

Fig.-3d-Rai-et-al-Nature-Communications-2020

Today’s post is the latest edition of my weekly recommended reads, which this week include Fate Therapeutics, COVID-19 updates, AAMC, and more including some great pubs such as one on 2 modes of PRC2 function. Also check out this handy resource: Helpful 2020 List of Stem Cell Journals and this blast from the past post of 10

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Weekly stem cell reads: diabetic wound healing, clinic bad outcomes, pubs list

CLOCK-function-in-mesenchymal-stem-cells

What’s new this week in terms of reads includes a stem cell/drug combo for diabetic wonderments healing, more documentation of patient harms from stem cell clinics, and a list of recommending papers. Adult stem cells/glaucoma drug combo promotes diabetic wound healing in mice From a team of my UC Davis School of Medicine colleagues led

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Weekly reads: FDA news, goosebump stem cells, MSCs, autophagy

Levy-et-al-MSCs-Science-Advances

Ready for the latest recommended weekly reads in the world of stem cells and the regenerative medicine space including a bunch of important new FDA posts & changes? This post has quite a lot on the FDA since it had a very big week with several new items of major importance to the cellular and regenerative

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