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Why CRISPR baby production (if it happened) was unethical & dangerous

Jiankui-He-who-claims-CRISPR-baby-production

Reports are out that a scientist in China has been working to make a CRISPR baby for some time and supposedly has made twin genetically modified babies. I see this work as unethical and dangerous. Just a couple years ago when I published my book GMO Sapiens on potential use of CRISPR in a heritable manner […]

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Quick Q&A with ViaCyte CEO on CRISPR-stem cell work

VC-01-post-implant-final1-e1503703572933, viacyte

We heard this week about the encouraging news of a new CRISPR-stem cell collaboration between stem cell biotech ViaCyte and CRISPR Therapeutics. The goal of the team is to make genetically engineered pancreatic derivatives from stem cells that would have a unique immune stealthiness. If such an approach was successful, patients would not need to

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Vampire facial update: Kardashian has regrets, others maybe infections

vampire facials

What the devil is a vampire facial? I first heard about the vampire facial, sometimes also called a “vampire facelift” when professional celebrity Kim Kardashian reportedly got one. I weighed in on that five years ago here. There was some question in how this procedure was portrayed as to whether it involved stem cells, which

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Fun pictures & 7 observations on the country from Australia trip

Melbourne-The-Lanes

What’s Australia like from the science to the country? I enjoyed the ISSCR2018 Annual Meeting in Melbourne on stem cells and regenerative medicine a few weeks back(here is a post on the some of the notable science from Day 1), but I also got a chance to get to know Australia a bit too. Below I have

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Clinic biz US Stem Cell reports SEC subpoena, adding to uncertainty on its future

US-Stem-Cell-Clinic

The last few years for the publicly-traded stem cell clinic biz, US Stem Cell, Inc., which goes by the ticker $USRM, have seemed like a rollercoaster to me as an observer. I can see four main areas of news that to me make the future seem uncertain for this firm. First, the US Stem was linked to the

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Journal club: Jaenisch lab paper on epigenetic CRISPR-Cas9 rescue of Fragile X in a dish

Liu-et-al.-Figure-6C-Fragile-X-CRISPR-Cell-e1519673510685

There’s much more to CRISPR-Cas9 than just gene editing and a new paper from the lab of Rudy Jaenisch in Cell highlights that in an exciting way. It reports epigenetic reversal of a Fragile X Syndrome phenotype in induced pluripotent stem cell (IPSC) neurons. Fragile X Syndrome is a neurological disorder in boys resulting from CGG repeat

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Animated map video shows wildfire spread of US stem cell clinics lacking FDA approval

stem-cell-clinic-animated-map-2010

There are now so many clinics selling non-FDA approved stem cell offerings across the U.S. that tens or hundreds of thousands of patients are at risk. How did we get here? What if we had a way of understanding how stem cell clinics spread across the U.S. in the first place? For example, an animated

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