Hank Greely over at The Center for Law and Biosciences at Stanford Law School was one of the participants in the recent Napa meeting on approaches to human germline genetic modification. Hank was also one of the authors on the resulting position paper in Science with David Baltimore as first author (here). Now Hank, pictured below, […]
Hank Greely Human Germline Modification Post Read More »
We’ve all heard the human embryo editing rumors. There is a sense that human embryos have already been CRISPR’d. Rumors are rumors and they may mean not a whole lot, but there definitely is a huge buzz on this right now both in a positive sense and with concern. The excitement is over the power of
Concerns flying on human embryo editing papers Read More »
CRISPR Cas9 is a relatively new, powerful approach to gene editing and genetic modification more generally. In the relatively short window of time in which this technology has been widely available for gene editing applications it has already evolved rapidly to become more powerful. Here are some new papers of interest on this technology. With
5 new cool papers on CRISPR Cas9 gene editing Read More »
The day after Easter and thoughts might turn to all those chocolate bunnies, eggs, etc…..leading to a question: is death by chocolate possible? What is the amount of chocolate you or I would have to eat in order to die? Could we even get close on a holiday like Halloween or Easter? It seems like
Death by chocolate? Let’s crunch the numbers for people Read More »
Should we be using the term ‘genetically modified human’ in discussions of heritable use of CRISPR in people? During the still ongoing discussions of genetic modification in the human germline and potentially in actual human beings in the future, an interesting, but difficult question has emerged: What words or names would be most appropriate for
Is ‘genetically modified human’ a loaded name? Read More »
Over at Practical Ethics they are calling for an almost Spock-like, emotion-free, and logical approach to the topic of heritable human genetic modification. Sounds good in principle, right? Well, unfortunately it fails in execution in their essay. The authors of “Editing the germline – a time for reason, not emotion” seem to include Chris Gyngell, Tom
Practical Plan for Managing Human Germline Genetic Modification CRISPR-Cas9 gene editing technology is a game changer on many levels both inside and soon outside the lab. There is a growing sense of urgency amongst biomedical scientists to take a proactive approach to current and future use of CRISPR technology in human germ cells and embryos.
If you work in academia and on grants, hen you might have been getting that grant Möbius strip, hamster wheel, Groundhog Day kind of feeling… The funding rate for the key so-called “R01” NIH laboratory biomedical grant has never been lower. In the long run, R01s are crucial to the everyday running of most biomedical
Got that grant hamster wheel feeling? Read More »
Discussion of concerns over heritable human genetic modification has spiked in 2015. This dialogue is a good thing, but is it in a sense too late? Are genetically modified (GM) people a foregone conclusion? Rumors are swirling that upwards of four papers reporting production of GM human embryos are in various stages of review at high-profile
Genetic Modification of Humans Now Inevitable? Read More »
By Jane Langille A few weeks ago, I wrote to Dr. Paul Knoepfler after reading his book Stem Cells: An Insider’s Guide because I was intrigued by his stem cell theory of aging. I wondered if his theory might mean that someone who mobilized and donated hematopoietic cells might be shortening their own lifetime supply. After
Risks for Healthy PBSC Donors? One Family’s Powerful Experience Read More »