Search Results for: rmat

Dedifferentiation of neurons & astrocytes into glioma forming cells

A team from the Salk Institute in La Jolla led by Inder Verma has reported dedifferentiation in a paper in Science some important findings that I believe make their paper in the top 10 as a candidate for paper of the year. The paper, entitled “Dedifferentiation of Neurons and Astrocytes by Oncogenes Can Induce Gliomas […]

Dedifferentiation of neurons & astrocytes into glioma forming cells Read More »

Will stem cell clinic Celltex reinvent itself after game-changing FDA warning letter?

The FDA warning letter that Celltex received in late September (but that just went public yesterday–see my initial reaction here) is a possible game-changer for that company in my opinion. Why? The letter outlined in great detail the FDA’s concerns with how Celltex manufactures its stem cell product ranging from lack of documentation to concerns about aseptic/sterile

Will stem cell clinic Celltex reinvent itself after game-changing FDA warning letter? Read More »

Celltex & its IRB provider both get serious FDA warning letters: Celltex response to my inquiry

Sugarland, Texas stem cell clinic, Celltex, is most well known for having done the stem cell treatment on Texas Governor Rick Perry. What’s up with Celltex this week? There has a lot of talk behind the scenes that something big has happened. Very recently Celltex put out a PR recently saying it had received a

Celltex & its IRB provider both get serious FDA warning letters: Celltex response to my inquiry Read More »

How did Japan’s top newspaper get tricked about iPS cells by Moriguchi?

How could the biggest newspaper in Japan, Yomiuri, get so badly tricked without even trying to verify facts prior to splashing it across their front page? A commenter on this blog named Mulboyne says that competing newspaper Mainichi was offered the Moriguchi story but solid investigative reporting made them decline it. Here’s the quote: “The

How did Japan’s top newspaper get tricked about iPS cells by Moriguchi? Read More »

Yomiuri Shimbun, Japan’s biggest newspaper, publishes front page apology on bogus iPS cell story; Moriguchi still claims his story is factual

Japan’s biggest daily newspaper, Yomiuri Shimbun, made international news when it reported a few days ago that iPS cells had been transplanted into human patients by Hisashi Moriguchi. In this morning’s paper, Yomiuri Shimbun issued a painful front page admission (happily reported by competing paper The Asahi Shimbun) of publishing false information about the alleged transplants, which

Yomiuri Shimbun, Japan’s biggest newspaper, publishes front page apology on bogus iPS cell story; Moriguchi still claims his story is factual Read More »

Major Japanese newspaper reports iPS cells already transplanted into human patients at Harvard

iPS-cell-headline-clip1

It seems like just yesterday I was blogging about how concerned I was that iPS cells might be used in early phase human clinical trials as early as next year and that would be high risk given safety concerns about iPS cells. Oh, it was yesterday. Now today….. Yomiuri Shimbun, one of the top newspapers

Major Japanese newspaper reports iPS cells already transplanted into human patients at Harvard Read More »

iPS cells are similar to cancer cells paper, part 2: unsettled reviewers

I’m a fan of iPS cells, but my lab has been concerned about the similarities between induced pluripotency and cancer formation for many years. We just now published a paper that directly addressed the similarities of cancer and iPS cell transcriptomes. These are cause for concern and need to be faced as we contemplate clinical

iPS cells are similar to cancer cells paper, part 2: unsettled reviewers Read More »