Search Results for: us stem cell

Blog readers investigate BioGatekeeper, the Yamanaka patent challenger

Nobel-Lawsuit

Who is trying, via the name BioGatekeeper, Inc., to nullify Yamanaka’s patent on cellular reprogramming to produce induced pluripotent stem (iPS) cells? The readers of this blog never cease to amaze me. What an informed, energetic, bright group. Within just days they may have collectively shed some light on an intriguing mystery in the stem cell field surrounding the […]

Blog readers investigate BioGatekeeper, the Yamanaka patent challenger Read More »

23andMe and the FDA: Perspectives on Warning Letter

23andMe

What’s the deal with this week’s FDA Warning Letter to 23andMe? First some background. I’m a researcher who studies stem and cancer cell genomics and epigenomics. I’m also a human being who has battled prostate cancer and is curious about my genome. With this background, I decided some time ago to take the plunge and experience what

23andMe and the FDA: Perspectives on Warning Letter Read More »

Interview with Regenerative Surgeon, Dr. Allan Wu

Over the last few weeks, I have enjoyed talking with and interviewing Dr. Allan Wu, of The Morrow Institute on stem cell cosmetic procedures. I was impressed greatly by his talk at the World Stem Cell Summit last year. Dr. Wu is a fellowship trained Surgical Molecular Biologist with a background in Molecular Embryology and a board

Interview with Regenerative Surgeon, Dr. Allan Wu Read More »

The Moriguchi iPS transplant fable: key lessons & where do we go from here

More and more evidence is accumulating that the alleged iPS cell transplantation in human patients by Dr. Hisashi Moriguchi was bunk. Nature today has a piece out today on the story providing more quotes about the case that suggest the whole thing was made up. Rather than re-hash all the details, in this post I’m going

The Moriguchi iPS transplant fable: key lessons & where do we go from here Read More »

NASA’s wickedly up & down week: broader lessons about science & medicine

All science, whether biology or physics, whether microscopic or at the solar system level, is about experiments. Sometimes we as a society forget that. In fact, experiments are at the heart of investigations as diverse as studying cells to exploring space to medical treatments. For NASA, the last week has been a tale of two

NASA’s wickedly up & down week: broader lessons about science & medicine Read More »

2025 PRP fact-check and review: cost and possible benefits

PRP-Platelet-Rich-Plasma-being-injected-into-a-hand

Platelet-rich plasma or PRP has become one of the most commonly used regenerative products at unproven clinics. The orthopedics departments at many universities are now offering PRP as well. What is behind this trend? How much data are there to back up all this enthusiasm for platelet-rich plasma? The goal of this post is to

2025 PRP fact-check and review: cost and possible benefits Read More »

Perspectives as Charles Brenner challenges David Sinclair on longevity claims

Charles Brenner, David Sinclair

Professor Charles Brenner of City of Hope does great research, but I also applaud his efforts against longevity hype. Recently, Brenner and James Timmons publicly questioned some of the work of Harvard Professor David Sinclair. It’s a notable case of academics intensely disagreeing in the public space. Background While it’s interesting, it’s also a somewhat

Perspectives as Charles Brenner challenges David Sinclair on longevity claims Read More »

In landmark, FDA approves first MSC therapy, Mesoblast’s Ryoncil for GvHD

mesoblast ceo dr silvio itescu

In a landmark decision, today the FDA approved Ryoncil from Mesoblast for GvHD. This is the first time the FDA has approved a mescenchymal stromal/stem cell or MSC therapy of any kind. There have been many ups and downs for Mesoblast toward this approval of Ryoncil or remestemcel-L, an allogeneic marrow MSC product. See my

In landmark, FDA approves first MSC therapy, Mesoblast’s Ryoncil for GvHD Read More »